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Activating Transcription Factor 6α Governs Stress-Adaptive Pancreatic β-Cell Mass Expansion by Coordinating Proliferation and Survival.

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Title: Activating Transcription Factor 6α Governs Stress-Adaptive Pancreatic β-Cell Mass Expansion by Coordinating Proliferation and Survival.
Authors: Otani D; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Murakami T; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Fauzi M; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Botagarova A; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Sekito S; Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, Tsu, Japan., Tatsuoka H; Research and Development Department, General Incorporated Association Kansai Healthcare Science Informatics, Kyoto, Japan., Tokumoto S; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Usui R; Center for Diabetes, Endocrinology and Metabolism, Kansai Electric Power Hospital, Osaka, Japan., Ogura M; Diabetes Center, National Hospital Organization Kyoto Medical Center, Kyoto, Japan., Toyoda T; Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Murakawa Y; Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Yabe D; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan., Inagaki N; Medical Research Institute, Kitano Hospital, PIIF Tazuke-Kofukai, Osaka, Japan.
Source: Diabetes [Diabetes] 2026 Jul 01; Vol. 75 (7), pp. 1201-1209.
Publication Type: Journal Article
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Activating Transcription Factor 6α Governs Stress-Adaptive Pancreatic β-Cell Mass Expansion by Coordinating Proliferation and Survival.
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  Data: <searchLink fieldCode="AU" term="%22Otani+D%22">Otani D</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+T%22">Murakami T</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Fauzi+M%22">Fauzi M</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Botagarova+A%22">Botagarova A</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Sekito+S%22">Sekito S</searchLink>; Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, Tsu, Japan.<br /><searchLink fieldCode="AU" term="%22Tatsuoka+H%22">Tatsuoka H</searchLink>; Research and Development Department, General Incorporated Association Kansai Healthcare Science Informatics, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Tokumoto+S%22">Tokumoto S</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Usui+R%22">Usui R</searchLink>; Center for Diabetes, Endocrinology and Metabolism, Kansai Electric Power Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ogura+M%22">Ogura M</searchLink>; Diabetes Center, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Toyoda+T%22">Toyoda T</searchLink>; Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Murakawa+Y%22">Murakawa Y</searchLink>; Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Yabe+D%22">Yabe D</searchLink>; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Inagaki+N%22">Inagaki N</searchLink>; Medical Research Institute, Kitano Hospital, PIIF Tazuke-Kofukai, Osaka, Japan.
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  Data: <searchLink fieldCode="JN" term="%220372763%22">Diabetes</searchLink> [Diabetes] 2026 Jul 01; Vol. 75 (7), pp. 1201-1209.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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