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Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multi-country Azithromycin Prevention in Labor Use Study (A-PLUS).

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Title: Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multi-country Azithromycin Prevention in Labor Use Study (A-PLUS).
Authors: Hibberd PL; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America., Kim JH; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America., Trotta M; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America., Leal SM; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Aceituno A; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America., Ward DV; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, United States of America., Patel A; Lata Medical Research Foundation, Nagpur, India.; Datta Meghe Institute of Higher Education and Research, Sawangi, India., Subramaniam A; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Carlo WA; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Ahmed I; Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan., Saleem S; Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan., Billah SM; International Centre for Diarrhoeal Disease Research (icddr, b), Dhaka, Bangladesh.; University of Sydney, Sydney, Australia., Haque R; International Centre for Diarrhoeal Disease Research (icddr, b), Dhaka, Bangladesh., Mazariegos M; Instituto de Nutrición de Centroamérica y Panamá, Guatemala City, Guatemala., Esamai F; Moi University School of Medicine, Eldoret, Kenya., Somannavar MS; KLE Academy Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India., Goudar SS; KLE Academy Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India., Chomba E; University of Zambia University Teaching Hospital, Lusaka, Zambia., Mwenchanya M; University of Zambia University Teaching Hospital, Lusaka, Zambia., Lokangaka A; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo., Tshefu A; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo., Goldenberg RL; Department of Obstetrics and Gynecology, Columbia University School of Medicine, New York, United States of America., Bauserman M; Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America., Krebs NF; University of Colorado School of Medicine, Denver, Colorado, United States of America., Bucher S; Indiana School of Public Health, Indiana University, Indianapolis, Indiana, United States of America., Derman RJ; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America., Petri WA; Department of Medicine, University of Virginia, Charlottesville, Virigina, United States of America., Koso-Thomas M; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, United States of America., Babineau DC; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America., McClure EM; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America., Tita ATN; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Source: PloS one [PLoS One] 2026 Apr 17; Vol. 21 (4), pp. e0346174. Date of Electronic Publication: 2026 Apr 17 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multi-country Azithromycin Prevention in Labor Use Study (A-PLUS).
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  Data: <searchLink fieldCode="AU" term="%22Hibberd+PL%22">Hibberd PL</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Trotta+M%22">Trotta M</searchLink>; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Leal+SM%22">Leal SM</searchLink>; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Aceituno+A%22">Aceituno A</searchLink>; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Ward+DV%22">Ward DV</searchLink>; Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Patel+A%22">Patel A</searchLink>; Lata Medical Research Foundation, Nagpur, India.; Datta Meghe Institute of Higher Education and Research, Sawangi, India.<br /><searchLink fieldCode="AU" term="%22Subramaniam+A%22">Subramaniam A</searchLink>; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Carlo+WA%22">Carlo WA</searchLink>; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Ahmed+I%22">Ahmed I</searchLink>; Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Saleem+S%22">Saleem S</searchLink>; Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Billah+SM%22">Billah SM</searchLink>; International Centre for Diarrhoeal Disease Research (icddr, b), Dhaka, Bangladesh.; University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Haque+R%22">Haque R</searchLink>; International Centre for Diarrhoeal Disease Research (icddr, b), Dhaka, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Mazariegos+M%22">Mazariegos M</searchLink>; Instituto de Nutrición de Centroamérica y Panamá, Guatemala City, Guatemala.<br /><searchLink fieldCode="AU" term="%22Esamai+F%22">Esamai F</searchLink>; Moi University School of Medicine, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Somannavar+MS%22">Somannavar MS</searchLink>; KLE Academy Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Goudar+SS%22">Goudar SS</searchLink>; KLE Academy Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Chomba+E%22">Chomba E</searchLink>; University of Zambia University Teaching Hospital, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Mwenchanya+M%22">Mwenchanya M</searchLink>; University of Zambia University Teaching Hospital, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Lokangaka+A%22">Lokangaka A</searchLink>; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.<br /><searchLink fieldCode="AU" term="%22Tshefu+A%22">Tshefu A</searchLink>; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.<br /><searchLink fieldCode="AU" term="%22Goldenberg+RL%22">Goldenberg RL</searchLink>; Department of Obstetrics and Gynecology, Columbia University School of Medicine, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Bauserman+M%22">Bauserman M</searchLink>; Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Krebs+NF%22">Krebs NF</searchLink>; University of Colorado School of Medicine, Denver, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Bucher+S%22">Bucher S</searchLink>; Indiana School of Public Health, Indiana University, Indianapolis, Indiana, United States of America.<br /><searchLink fieldCode="AU" term="%22Derman+RJ%22">Derman RJ</searchLink>; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Petri+WA%22">Petri WA</searchLink>; Department of Medicine, University of Virginia, Charlottesville, Virigina, United States of America.<br /><searchLink fieldCode="AU" term="%22Koso-Thomas+M%22">Koso-Thomas M</searchLink>; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Babineau+DC%22">Babineau DC</searchLink>; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22McClure+EM%22">McClure EM</searchLink>; Social, Statistical and Environmental Health Sciences, RTI International, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Tita+ATN%22">Tita ATN</searchLink>; Department of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Apr 17; Vol. 21 (4), pp. e0346174. <i>Date of Electronic Publication: </i>2026 Apr 17 (<i>Print Publication: </i>2026).
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