Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge.
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| Title: | Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge. |
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| Authors: | Makuyana N; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; MRC Laboratory of Molecular Biology, Cambridge, UK., Seldeslachts L; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Michiels L; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Burton OT; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Hernandez AR; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Life Sciences, Imperial College London, London, UK., Ghodsinia A; Department of Pathology, University of Cambridge, Cambridge, UK., Rahman E; National Heart & Lung Institute, Imperial College London, London, UK., Kops LM; Department of Pathology, University of Cambridge, Cambridge, UK., Singh K; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; Medical Cell Biology, Uppsala University, Uppsala, Sweden., Naranjo F; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Ali M; Department of Pathology, University of Cambridge, Cambridge, UK., Dashwood A; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Achkir M; Department of Pathology, University of Cambridge, Cambridge, UK., Kouser L; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Lienart S; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Guillaume S; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Naesens L; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium., Linterman MA; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; Malaghan Institute of Medical Research, Wellington, Aotearoa New Zealand., Wauters J; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium., Joulia R; National Heart & Lung Institute, Imperial College London, London, UK., Humblet-Baron S; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium., Vande Velde G; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Dooley J; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK., Liston A; Department of Pathology, University of Cambridge, Cambridge, UK. |
| Source: | Science immunology [Sci Immunol] 2026 Apr 17; Vol. 11 (118), pp. eadv7969. Date of Electronic Publication: 2026 Apr 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41996474 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Makuyana+N%22">Makuyana N</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; MRC Laboratory of Molecular Biology, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Seldeslachts+L%22">Seldeslachts L</searchLink>; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Michiels+L%22">Michiels L</searchLink>; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Burton+OT%22">Burton OT</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hernandez+AR%22">Hernandez AR</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ghodsinia+A%22">Ghodsinia A</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Rahman+E%22">Rahman E</searchLink>; National Heart & Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kops+LM%22">Kops LM</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Singh+K%22">Singh K</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; Medical Cell Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Naranjo+F%22">Naranjo F</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ali+M%22">Ali M</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Dashwood+A%22">Dashwood A</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Achkir+M%22">Achkir M</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kouser+L%22">Kouser L</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lienart+S%22">Lienart S</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Guillaume+S%22">Guillaume S</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Naesens+L%22">Naesens L</searchLink>; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Linterman+MA%22">Linterman MA</searchLink>; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.; Malaghan Institute of Medical Research, Wellington, Aotearoa New Zealand.<br /><searchLink fieldCode="AU" term="%22Wauters+J%22">Wauters J</searchLink>; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Joulia+R%22">Joulia R</searchLink>; National Heart & Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Humblet-Baron+S%22">Humblet-Baron S</searchLink>; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vande+Velde+G%22">Vande Velde G</searchLink>; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Dooley+J%22">Dooley J</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Lymphocyte Signalling Department, Babraham Institute Babraham Research Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Liston+A%22">Liston A</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2026 Apr 17; Vol. 11 (118), pp. eadv7969. <i>Date of Electronic Publication: </i>2026 Apr 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101688624 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-9468 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224709468%22">24709468 </searchLink><i>NLM ISO Abbreviation: </i>Sci Immunol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41996474 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/sciimmunol.adv7969 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eadv7969 Titles: – TitleFull: Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Makuyana N – PersonEntity: Name: NameFull: Seldeslachts L – PersonEntity: Name: NameFull: Michiels L – PersonEntity: Name: NameFull: Burton OT – PersonEntity: Name: NameFull: Hernandez AR – PersonEntity: Name: NameFull: Ghodsinia A – PersonEntity: Name: NameFull: Rahman E – PersonEntity: Name: NameFull: Kops LM – PersonEntity: Name: NameFull: Singh K – PersonEntity: Name: NameFull: Naranjo F – PersonEntity: Name: NameFull: Ali M – PersonEntity: Name: NameFull: Dashwood A – PersonEntity: Name: NameFull: Achkir M – PersonEntity: Name: NameFull: Kouser L – PersonEntity: Name: NameFull: Lienart S – PersonEntity: Name: NameFull: Guillaume S – PersonEntity: Name: NameFull: Naesens L – PersonEntity: Name: NameFull: Linterman MA – PersonEntity: Name: NameFull: Wauters J – PersonEntity: Name: NameFull: Joulia R – PersonEntity: Name: NameFull: Humblet-Baron S – PersonEntity: Name: NameFull: Vande Velde G – PersonEntity: Name: NameFull: Dooley J – PersonEntity: Name: NameFull: Liston A IsPartOfRelationships: – BibEntity: Dates: – D: 17 M: 04 Text: 2026 Apr 17 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2470-9468 Numbering: – Type: volume Value: 11 – Type: issue Value: 118 Titles: – TitleFull: Science immunology Type: main |
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