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The role of growth factors in peripheral nerve regeneration and opportunities for next-generation biological therapeutics.

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Title: The role of growth factors in peripheral nerve regeneration and opportunities for next-generation biological therapeutics.
Authors: Alpizar Vargas V; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA., Shultz RB; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Axonova Medical, Inc., Philadelphia, PA, USA., Laimo FA; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cullen DK; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: dkacy@pennmedicine.upenn.edu., Lee HH; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Orthopedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: Hannah.Lee1@pennmedicine.upenn.edu.
Source: Biomaterials [Biomaterials] 2026 Oct; Vol. 333, pp. 124206. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Alpizar+Vargas+V%22">Alpizar Vargas V</searchLink>; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shultz+RB%22">Shultz RB</searchLink>; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Axonova Medical, Inc., Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Laimo+FA%22">Laimo FA</searchLink>; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cullen+DK%22">Cullen DK</searchLink>; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: dkacy@pennmedicine.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Lee+HH%22">Lee HH</searchLink>; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA; Department of Orthopedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: Hannah.Lee1@pennmedicine.upenn.edu.
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      – TitleFull: The role of growth factors in peripheral nerve regeneration and opportunities for next-generation biological therapeutics.
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              Text: 2026 Oct
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