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Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models.

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Title: Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models.
Authors: Yang YP; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA., Nicol CJB; Departments of Pathology & Molecular Medicine and Biomedical & Molecular Sciences, Cancer Biology and Genetics Division, Sinclair Cancer Research Institute, Queen's University, Kingston, ON, K7L 3N6, Canada., Yen C; Department of International Business, Ming Chuan University, Taipei, 111, Taiwan., Chiang MC; Department of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City, 242, Taiwan. Electronic address: 089034@mail.fju.edu.tw.
Source: Experimental cell research [Exp Cell Res] 2026 Jun 15; Vol. 459 (2), pp. 115030. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models.
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  Data: <searchLink fieldCode="AU" term="%22Yang+YP%22">Yang YP</searchLink>; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Nicol+CJB%22">Nicol CJB</searchLink>; Departments of Pathology & Molecular Medicine and Biomedical & Molecular Sciences, Cancer Biology and Genetics Division, Sinclair Cancer Research Institute, Queen's University, Kingston, ON, K7L 3N6, Canada.<br /><searchLink fieldCode="AU" term="%22Yen+C%22">Yen C</searchLink>; Department of International Business, Ming Chuan University, Taipei, 111, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+MC%22">Chiang MC</searchLink>; Department of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City, 242, Taiwan. Electronic address: 089034@mail.fju.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%220373226%22">Experimental cell research</searchLink> [Exp Cell Res] 2026 Jun 15; Vol. 459 (2), pp. 115030. <i>Date of Electronic Publication: </i>2026 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0373226 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2422 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200144827%22">00144827 </searchLink><i>NLM ISO Abbreviation: </i>Exp Cell Res <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.yexcr.2026.115030
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      – Code: eng
        Text: English
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      – TitleFull: Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models.
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            NameFull: Nicol CJB
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              Text: 2026 Jun 15
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