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Decoding kratom: molecular mechanisms and epigenetic factors in use and dependence.

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Title: Decoding kratom: molecular mechanisms and epigenetic factors in use and dependence.
Authors: Misnan E; Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.; Universiti Malaya Centre for Addiction Science Studies (UMCAS), Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Hasbullah NZA; Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Abd Rashid R; Universiti Malaya Centre for Addiction Science Studies (UMCAS), Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.; Department of Psychological Medicine, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Mohd Shah A; Klinik Kesihatan Ayer Keroh, Jabatan Kesihatan Negeri Melaka, 75450, Melaka, Malaysia., Sim MS; Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. garethsim@um.edu.my.; Precision Medicine and Omics Centre (PrOmiC), Faculty of Pharmacy, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. garethsim@um.edu.my.
Source: Translational psychiatry [Transl Psychiatry] 2026 Apr 16; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Systematic Review; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2158-3188
DOI:10.1038/s41398-026-04022-5