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First-in-Human Study of CEB-01: Novel Loco-Regional SN-38-Releasing Membrane to Prevent Local Recurrence in Retroperitoneal Sarcomas.

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Title: First-in-Human Study of CEB-01: Novel Loco-Regional SN-38-Releasing Membrane to Prevent Local Recurrence in Retroperitoneal Sarcomas.
Authors: Gonzalez JA; Department of Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Sebio A; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. asebio@santpau.cat., Martin-Broto J; Medical Oncology Department, Hospital Universitario Fundación Jiménez Díaz and Villalba General Hospital, Madrid, Spain., Hindi N; Medical Oncology Department, Hospital Universitario Fundación Jiménez Díaz and Villalba General Hospital, Madrid, Spain., Villarejo-Campos P; Department of Surgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Jiménez M; Department of Surgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Díaz-Beveridge R; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain., Orbis Castellanos JF; Department of Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain., López Andújar R; Department of Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain., Álvarez Álvarez R; Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Asencio JM; Department of Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Serrano C; Medical Oncology Department, Hospital Universitario Vall d'Hebron, Vall d'Hebron Institute of Oncology, Barcelona, Spain., Rodríguez Conde N; Servicio de Cirugía General y Digestiva, Hospital Universitario Vall d'Hebron, Barcelona, Spain., Castro Boix S; Servicio de Cirugía General y Digestiva, Hospital Universitario Vall d'Hebron, Barcelona, Spain., Krauel L; Pediatric Surgery Department, SJD Barcelona Children's Hospital, Universitat de Barcelona, Barcelona, Spain., Colom Codina H; Pharmaceutical Technology & Physical-Chemistry Department, School of Pharmacy, University of Barcelona, Barcelona, Spain., Tornero García JA; Universitat Politècnica de Catalunya (UPC), Barcelona, Spain.; Cebiotex S.L., Barcelona, Spain., Lopera de Llanos E; Cebiotex S.L., Barcelona, Spain., Huguet Ninou A; Cebiotex S.L., Barcelona, Spain., Pérez Campos A; Cebiotex S.L., Barcelona, Spain., Gruber AK; Cebiotex S.L., Barcelona, Spain., López Pousa A; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Source: Annals of surgical oncology [Ann Surg Oncol] 2026 Aug; Vol. 33 (8), pp. 7677-7687. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: First-in-Human Study of CEB-01: Novel Loco-Regional SN-38-Releasing Membrane to Prevent Local Recurrence in Retroperitoneal Sarcomas.
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  Data: <searchLink fieldCode="AU" term="%22Gonzalez+JA%22">Gonzalez JA</searchLink>; Department of Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sebio+A%22">Sebio A</searchLink>; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. asebio@santpau.cat.<br /><searchLink fieldCode="AU" term="%22Martin-Broto+J%22">Martin-Broto J</searchLink>; Medical Oncology Department, Hospital Universitario Fundación Jiménez Díaz and Villalba General Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Hindi+N%22">Hindi N</searchLink>; Medical Oncology Department, Hospital Universitario Fundación Jiménez Díaz and Villalba General Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Villarejo-Campos+P%22">Villarejo-Campos P</searchLink>; Department of Surgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Jiménez+M%22">Jiménez M</searchLink>; Department of Surgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Díaz-Beveridge+R%22">Díaz-Beveridge R</searchLink>; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Orbis+Castellanos+JF%22">Orbis Castellanos JF</searchLink>; Department of Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22López+Andújar+R%22">López Andújar R</searchLink>; Department of Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+Álvarez+R%22">Álvarez Álvarez R</searchLink>; Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Asencio+JM%22">Asencio JM</searchLink>; Department of Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Serrano+C%22">Serrano C</searchLink>; Medical Oncology Department, Hospital Universitario Vall d'Hebron, Vall d'Hebron Institute of Oncology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+Conde+N%22">Rodríguez Conde N</searchLink>; Servicio de Cirugía General y Digestiva, Hospital Universitario Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Castro+Boix+S%22">Castro Boix S</searchLink>; Servicio de Cirugía General y Digestiva, Hospital Universitario Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Krauel+L%22">Krauel L</searchLink>; Pediatric Surgery Department, SJD Barcelona Children's Hospital, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Colom+Codina+H%22">Colom Codina H</searchLink>; Pharmaceutical Technology & Physical-Chemistry Department, School of Pharmacy, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tornero+García+JA%22">Tornero García JA</searchLink>; Universitat Politècnica de Catalunya (UPC), Barcelona, Spain.; Cebiotex S.L., Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lopera+de+Llanos+E%22">Lopera de Llanos E</searchLink>; Cebiotex S.L., Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Huguet+Ninou+A%22">Huguet Ninou A</searchLink>; Cebiotex S.L., Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez+Campos+A%22">Pérez Campos A</searchLink>; Cebiotex S.L., Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gruber+AK%22">Gruber AK</searchLink>; Cebiotex S.L., Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López+Pousa+A%22">López Pousa A</searchLink>; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
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  Data: <searchLink fieldCode="JN" term="%229420840%22">Annals of surgical oncology</searchLink> [Ann Surg Oncol] 2026 Aug; Vol. 33 (8), pp. 7677-7687. <i>Date of Electronic Publication: </i>2026 Apr 17.
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  Data: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9420840 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1534-4681 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210689265%22">10689265 </searchLink><i>NLM ISO Abbreviation: </i>Ann Surg Oncol <i>Subsets: </i>MEDLINE
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