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Loss of maternal PADI6 disrupts DNA methylation and genomic imprinting maintenance in late preimplantation mouse embryos.

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Title: Loss of maternal PADI6 disrupts DNA methylation and genomic imprinting maintenance in late preimplantation mouse embryos.
Authors: Giaccari C; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., Cecere F; UOS Laboratori di Ricerca e Biobanca, UOC Ricerca Clinica e Traslazionale, AORN Santobono-Pausilipon, Via Teresa Ravaschieri, 8, 80129, Naples, Italy., Pagano A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., D'Angelo E; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., Saadat A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy., Mele L; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., Salerno P; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy., Merla G; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.; Laboratory of Regulatory and Functional Genomics, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy., Cerrato F; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy., Riccio A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. andrea.riccio@unicampania.it.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy. andrea.riccio@unicampania.it.
Source: Epigenetics & chromatin [Epigenetics Chromatin] 2026 Apr 17; Vol. 19 (1). Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101471619 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8935 (Electronic) Linking ISSN: 17568935 NLM ISO Abbreviation: Epigenetics Chromatin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Loss of maternal PADI6 disrupts DNA methylation and genomic imprinting maintenance in late preimplantation mouse embryos.
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  Data: <searchLink fieldCode="AU" term="%22Giaccari+C%22">Giaccari C</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Cecere+F%22">Cecere F</searchLink>; UOS Laboratori di Ricerca e Biobanca, UOC Ricerca Clinica e Traslazionale, AORN Santobono-Pausilipon, Via Teresa Ravaschieri, 8, 80129, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pagano+A%22">Pagano A</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.<br /><searchLink fieldCode="AU" term="%22D'Angelo+E%22">D'Angelo E</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Saadat+A%22">Saadat A</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Mele+L%22">Mele L</searchLink>; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Salerno+P%22">Salerno P</searchLink>; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Merla+G%22">Merla G</searchLink>; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.; Laboratory of Regulatory and Functional Genomics, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Cerrato+F%22">Cerrato F</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Riccio+A%22">Riccio A</searchLink>; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. andrea.riccio@unicampania.it.; Institute of Genetics and Biophysics (IGB) 'Adriano Buzzati-Traverso', Consiglio Nazionale delle Ricerche (CNR), Naples, Italy. andrea.riccio@unicampania.it.
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  Data: <searchLink fieldCode="JN" term="%22101471619%22">Epigenetics & chromatin</searchLink> [Epigenetics Chromatin] 2026 Apr 17; Vol. 19 (1). <i>Date of Electronic Publication: </i>2026 Apr 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101471619 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-8935 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217568935%22">17568935 </searchLink><i>NLM ISO Abbreviation: </i>Epigenetics Chromatin <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13072-026-00674-1
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        Text: English
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      – TitleFull: Loss of maternal PADI6 disrupts DNA methylation and genomic imprinting maintenance in late preimplantation mouse embryos.
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              Text: 2026 Apr 17
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