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Age-Appropriate Low Dosing for Food Protein-Induced Enterocolitis Syndrome Oral Food Challenges: Proposing a Standardized Approach.

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Title: Age-Appropriate Low Dosing for Food Protein-Induced Enterocolitis Syndrome Oral Food Challenges: Proposing a Standardized Approach.
Authors: Anvari S; Department of Pediatrics, Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex. Electronic address: Sara.Anvari@bcm.edu., Baker MG; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY., Bingemann T; Divisions of Allergy, Immunology and Rheumatology, and Pediatric Allergy and Immunology, University of Rochester, Rochester, NY., Bird JA; Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex., Brown-Whitehorn T; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., Cianferoni A; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., Durban R; Raquel Durban, LLC, Charlotte, NC., Gupta M; Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex., Hosein E; Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC., Konstantinou G; Department of Allergy and Clinical Immunology, 424 General Military Training Hospital, Thessaloniki, Greece., Leonard S; Division of Allergy and Immunology, University of California San Diego, Rady Children's Hospital, San Diego, Calif., Ruffner MA; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., Schaible A; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY., Scurlock AM; Division of Allergy and Immunology, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Ark., Varshney P; Division of Allergy and Immunology, Department of Pediatrics, Dell Children's Medical Center, Dell Medical School at The University of Texas at Austin, Austin, Tex., Muraro A; Food Allergy Referral Centre, Padua University Hospital, Padua, Italy., Fiocchi A; Allergy Unit, Pediatric Hospital Bambino Gesù IRCCS, Rome, Italy., Santos AF; Department of Women and Children's Health (Pediatric Allergy), Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom., Arasi S; Pediatric Allergology Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Vazquez-Ortiz M; Pediatric Allergy, Imperial College NHS Healthcare Trust, National Heart and Lung Institute, Imperial College London, London, United Kingdom., Morita H; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan; Allergy Center, National Center for Child Health and Development, Tokyo, Japan., Nomura I; Allergy Center, National Center for Child Health and Development, Tokyo, Japan; Division of Eosinophilic Gastrointestinal Disorders, National Research Institute for Child Health and Development, Tokyo, Japan., Upton JEM; Division of Immunology and Allergy, Department of Pediatrics, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada., Levin M; Division of Allergy and Asthma, University of Cape Town, Cape Town, South Africa., Lee E; Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney Children's Hospital Network, Sydney, New South Wales, Australia., Galvan C; Medical Director Emedic Salud, Allergy Department, Clinica Internacional, Lima, Peru., Hoyos-Bachiloglu R; Department of Pediatrics, Facultad de Medicina Clinica Alemana Universidad del Desarrollo, Santiago, Chile., Chatchatee P; Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Beyer K; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany; German Center for Child and Adolescent Health (DZKJ), Partner Site Berlin, Berlin, Germany., du Toit G; Department of Paediatric Allergy, Evelina London, Guy's and St Thomas' NHS Trust and King's College London, London, United Kingdom., Gonzalez-Delgado P; Allergy Department, Hospital General Universitario Dr Balmis, ISABIAL, Alicante, Spain; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain., Yin Wong LS; Khoo Teck Puat-University Children's Medical Institute, National University Health Systems, Singapore; Department of Paediatrics, National University of Singapore, Singapore., Groetch M; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY., Nowak-Wegrzyn A; Department of Pediatrics, Hassenfeld Children's Hospital, NYU Grossman School of Medicine, New York, NY; Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Source: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2026 Jul; Vol. 14 (7), pp. 1570-1588.e2. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Age-Appropriate Low Dosing for Food Protein-Induced Enterocolitis Syndrome Oral Food Challenges: Proposing a Standardized Approach.
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  Data: <searchLink fieldCode="AU" term="%22Anvari+S%22">Anvari S</searchLink>; Department of Pediatrics, Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex. Electronic address: Sara.Anvari@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Baker+MG%22">Baker MG</searchLink>; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Bingemann+T%22">Bingemann T</searchLink>; Divisions of Allergy, Immunology and Rheumatology, and Pediatric Allergy and Immunology, University of Rochester, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Bird+JA%22">Bird JA</searchLink>; Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex.<br /><searchLink fieldCode="AU" term="%22Brown-Whitehorn+T%22">Brown-Whitehorn T</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.<br /><searchLink fieldCode="AU" term="%22Cianferoni+A%22">Cianferoni A</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.<br /><searchLink fieldCode="AU" term="%22Durban+R%22">Durban R</searchLink>; Raquel Durban, LLC, Charlotte, NC.<br /><searchLink fieldCode="AU" term="%22Gupta+M%22">Gupta M</searchLink>; Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex.<br /><searchLink fieldCode="AU" term="%22Hosein+E%22">Hosein E</searchLink>; Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Konstantinou+G%22">Konstantinou G</searchLink>; Department of Allergy and Clinical Immunology, 424 General Military Training Hospital, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Leonard+S%22">Leonard S</searchLink>; Division of Allergy and Immunology, University of California San Diego, Rady Children's Hospital, San Diego, Calif.<br /><searchLink fieldCode="AU" term="%22Ruffner+MA%22">Ruffner MA</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.<br /><searchLink fieldCode="AU" term="%22Schaible+A%22">Schaible A</searchLink>; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Scurlock+AM%22">Scurlock AM</searchLink>; Division of Allergy and Immunology, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Ark.<br /><searchLink fieldCode="AU" term="%22Varshney+P%22">Varshney P</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Dell Children's Medical Center, Dell Medical School at The University of Texas at Austin, Austin, Tex.<br /><searchLink fieldCode="AU" term="%22Muraro+A%22">Muraro A</searchLink>; Food Allergy Referral Centre, Padua University Hospital, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Fiocchi+A%22">Fiocchi A</searchLink>; Allergy Unit, Pediatric Hospital Bambino Gesù IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Santos+AF%22">Santos AF</searchLink>; Department of Women and Children's Health (Pediatric Allergy), Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Arasi+S%22">Arasi S</searchLink>; Pediatric Allergology Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Vazquez-Ortiz+M%22">Vazquez-Ortiz M</searchLink>; Pediatric Allergy, Imperial College NHS Healthcare Trust, National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Morita+H%22">Morita H</searchLink>; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan; Allergy Center, National Center for Child Health and Development, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nomura+I%22">Nomura I</searchLink>; Allergy Center, National Center for Child Health and Development, Tokyo, Japan; Division of Eosinophilic Gastrointestinal Disorders, National Research Institute for Child Health and Development, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Upton+JEM%22">Upton JEM</searchLink>; Division of Immunology and Allergy, Department of Pediatrics, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Levin+M%22">Levin M</searchLink>; Division of Allergy and Asthma, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Lee+E%22">Lee E</searchLink>; Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney Children's Hospital Network, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Galvan+C%22">Galvan C</searchLink>; Medical Director Emedic Salud, Allergy Department, Clinica Internacional, Lima, Peru.<br /><searchLink fieldCode="AU" term="%22Hoyos-Bachiloglu+R%22">Hoyos-Bachiloglu R</searchLink>; Department of Pediatrics, Facultad de Medicina Clinica Alemana Universidad del Desarrollo, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Chatchatee+P%22">Chatchatee P</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Beyer+K%22">Beyer K</searchLink>; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany; German Center for Child and Adolescent Health (DZKJ), Partner Site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22du+Toit+G%22">du Toit G</searchLink>; Department of Paediatric Allergy, Evelina London, Guy's and St Thomas' NHS Trust and King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Delgado+P%22">Gonzalez-Delgado P</searchLink>; Allergy Department, Hospital General Universitario Dr Balmis, ISABIAL, Alicante, Spain; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Yin+Wong+LS%22">Yin Wong LS</searchLink>; Khoo Teck Puat-University Children's Medical Institute, National University Health Systems, Singapore; Department of Paediatrics, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Groetch+M%22">Groetch M</searchLink>; Elliot and Roslyn Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Jack and Lucy Clark Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Nowak-Wegrzyn+A%22">Nowak-Wegrzyn A</searchLink>; Department of Pediatrics, Hassenfeld Children's Hospital, NYU Grossman School of Medicine, New York, NY; Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
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  Data: <searchLink fieldCode="JN" term="%22101597220%22">The journal of allergy and clinical immunology. In practice</searchLink> [J Allergy Clin Immunol Pract] 2026 Jul; Vol. 14 (7), pp. 1570-1588.e2. <i>Date of Electronic Publication: </i>2026 Apr 16.
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