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Chromenone coupled to spiro[indene-2,3'-pyrrolizine]-1,3-diones as a novel class of α-glucosidase inhibitor.

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Title: Chromenone coupled to spiro[indene-2,3'-pyrrolizine]-1,3-diones as a novel class of α-glucosidase inhibitor.
Authors: Eisayi A; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran., Fathi A; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran., Ramezanpour S; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran., Eftekharian F; Internal Medicine Department, Jahrom University of Medical Sciences, Jahrom, Iran., Dastyafteh N; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Mahdavi M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Iraji A; Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: iraji@sums.ac.ir., Darvish F; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran. Electronic address: darvish@kntu.ac.ir.
Source: Bioorganic chemistry [Bioorg Chem] 2026 Jul 15; Vol. 176, pp. 109739. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Chromenone coupled to spiro[indene-2,3'-pyrrolizine]-1,3-diones as a novel class of α-glucosidase inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Eisayi+A%22">Eisayi A</searchLink>; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran.<br /><searchLink fieldCode="AU" term="%22Fathi+A%22">Fathi A</searchLink>; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran.<br /><searchLink fieldCode="AU" term="%22Ramezanpour+S%22">Ramezanpour S</searchLink>; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran.<br /><searchLink fieldCode="AU" term="%22Eftekharian+F%22">Eftekharian F</searchLink>; Internal Medicine Department, Jahrom University of Medical Sciences, Jahrom, Iran.<br /><searchLink fieldCode="AU" term="%22Dastyafteh+N%22">Dastyafteh N</searchLink>; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Mahdavi+M%22">Mahdavi M</searchLink>; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Iraji+A%22">Iraji A</searchLink>; Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: iraji@sums.ac.ir.<br /><searchLink fieldCode="AU" term="%22Darvish+F%22">Darvish F</searchLink>; Department of Chemistry, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran 19697-64499, Iran. Electronic address: darvish@kntu.ac.ir.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2026 Jul 15; Vol. 176, pp. 109739. <i>Date of Electronic Publication: </i>2026 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bioorg.2026.109739
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              Text: 2026 Jul 15
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