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Circulating Endotrophin Predicts Myocardial Fibrosis Burden and Is Sensitive to Antifibrotic Therapy.

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Title: Circulating Endotrophin Predicts Myocardial Fibrosis Burden and Is Sensitive to Antifibrotic Therapy.
Authors: Black N; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Lewis G; Liverpool University Hospitals NHS Foundation Trust, Royal Liverpool University Hospital, Liverpool, United Kingdom., Soltani F; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Dodd S; Department of Health Data Science, Institute of Population Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom., Williams SG; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Schelbert EB; Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA., Laursen C; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Nordic Bioscience A/S, Herlev, Denmark., Angeli E; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Nordic Bioscience A/S, Herlev, Denmark., Reese-Petersen AL; Nordic Bioscience A/S, Herlev, Denmark., Karsdal M; Nordic Bioscience A/S, Herlev, Denmark., Genovese F; Nordic Bioscience A/S, Herlev, Denmark., Miller CA; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom. Electronic address: Christopher.miller@manchester.ac.uk.
Source: JACC. Advances [JACC Adv] 2026 May; Vol. 5 (5), pp. 102738. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918419284106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-963X (Electronic) Linking ISSN: 2772963X NLM ISO Abbreviation: JACC Adv Subsets: PubMed not MEDLINE
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  Data: Circulating Endotrophin Predicts Myocardial Fibrosis Burden and Is Sensitive to Antifibrotic Therapy.
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  Data: <searchLink fieldCode="AU" term="%22Black+N%22">Black N</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lewis+G%22">Lewis G</searchLink>; Liverpool University Hospitals NHS Foundation Trust, Royal Liverpool University Hospital, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Soltani+F%22">Soltani F</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dodd+S%22">Dodd S</searchLink>; Department of Health Data Science, Institute of Population Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Williams+SG%22">Williams SG</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schelbert+EB%22">Schelbert EB</searchLink>; Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Laursen+C%22">Laursen C</searchLink>; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Nordic Bioscience A/S, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Angeli+E%22">Angeli E</searchLink>; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Nordic Bioscience A/S, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Reese-Petersen+AL%22">Reese-Petersen AL</searchLink>; Nordic Bioscience A/S, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Karsdal+M%22">Karsdal M</searchLink>; Nordic Bioscience A/S, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Genovese+F%22">Genovese F</searchLink>; Nordic Bioscience A/S, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Miller+CA%22">Miller CA</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom; Manchester University NHS Foundation Trust, Manchester, United Kingdom. Electronic address: Christopher.miller@manchester.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229918419284106676%22">JACC. Advances</searchLink> [JACC Adv] 2026 May; Vol. 5 (5), pp. 102738. <i>Date of Electronic Publication: </i>2026 Apr 17.
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