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PD-L1 CPS in gastroesophageal cancer: differences in routine care versus Checkmate 649 and implications for biopsy-site choice and assay standardisation.

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Title: PD-L1 CPS in gastroesophageal cancer: differences in routine care versus Checkmate 649 and implications for biopsy-site choice and assay standardisation.
Authors: Flanders L; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Savy T; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK., Ficial M; Barts Health NHS Trust, Department of Cellular Pathology, London, UK., Al-Ghraibawi N; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Barber L; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK., Slater S; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Pihlak R; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Propper D; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.; Barts Cancer Institute, Centre for Tumour Microenvironment, Queen Mary University of London, London, UK., Begum S; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Rodriguez-Justo M; University College London Hospital, Department of Pathology, London, UK., Gerlinger M; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK. m.gerlinger@qmul.ac.uk.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK. m.gerlinger@qmul.ac.uk.
Source: British journal of cancer [Br J Cancer] 2026 Jul; Vol. 135 (2), pp. 232-239. Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PD-L1 CPS in gastroesophageal cancer: differences in routine care versus Checkmate 649 and implications for biopsy-site choice and assay standardisation.
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  Data: <searchLink fieldCode="AU" term="%22Flanders+L%22">Flanders L</searchLink>; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Savy+T%22">Savy T</searchLink>; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ficial+M%22">Ficial M</searchLink>; Barts Health NHS Trust, Department of Cellular Pathology, London, UK.<br /><searchLink fieldCode="AU" term="%22Al-Ghraibawi+N%22">Al-Ghraibawi N</searchLink>; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Barber+L%22">Barber L</searchLink>; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Slater+S%22">Slater S</searchLink>; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Pihlak+R%22">Pihlak R</searchLink>; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Propper+D%22">Propper D</searchLink>; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.; Barts Cancer Institute, Centre for Tumour Microenvironment, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Begum+S%22">Begum S</searchLink>; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Justo+M%22">Rodriguez-Justo M</searchLink>; University College London Hospital, Department of Pathology, London, UK.<br /><searchLink fieldCode="AU" term="%22Gerlinger+M%22">Gerlinger M</searchLink>; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK. m.gerlinger@qmul.ac.uk.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK. m.gerlinger@qmul.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2026 Jul; Vol. 135 (2), pp. 232-239. <i>Date of Electronic Publication: </i>2026 Apr 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41416-026-03404-2
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              Text: 2026 Jul
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