Does the use of laser therapy enhance healing and reduce the size of periapical lesions? A systematic review and meta-analysis.

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Title: Does the use of laser therapy enhance healing and reduce the size of periapical lesions? A systematic review and meta-analysis.
Authors: Creazzo G; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: gucreazzo@usp.br., Salmon B; Université Paris Cité and Sorbonne Paris Nord, Inserm UMR 1333, Oral Health, F-92120 Montrouge, France; Dental Medicine Department, Bretonneau University Hospital, AP-HP, F-75014 Paris, France. Electronic address: benjamin.salmon@u-paris.fr., Almeida J; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: almeida.juliana@usp.br., Faria-E-Silva AL; Department of Dentistry, Dental School, Laval University, Québec QC, Canada. Electronic address: andre-luis.faria-e-silva@fmd.ulaval.ca., Lopes-Olhê FC; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: fabiane.lopes@usp.br., Souza-Gabriel AE; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: aline.gabriel@forp.usp.br., Sousa-Neto MD; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: sousanet@forp.usp.br., Candemil AP; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: amandacandemil@usp.br.
Source: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2026 Jun; Vol. 59, pp. 105472. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101226123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1597 (Electronic) Linking ISSN: 15721000 NLM ISO Abbreviation: Photodiagnosis Photodyn Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Does the use of laser therapy enhance healing and reduce the size of periapical lesions? A systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Creazzo+G%22">Creazzo G</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: gucreazzo@usp.br.<br /><searchLink fieldCode="AU" term="%22Salmon+B%22">Salmon B</searchLink>; Université Paris Cité and Sorbonne Paris Nord, Inserm UMR 1333, Oral Health, F-92120 Montrouge, France; Dental Medicine Department, Bretonneau University Hospital, AP-HP, F-75014 Paris, France. Electronic address: benjamin.salmon@u-paris.fr.<br /><searchLink fieldCode="AU" term="%22Almeida+J%22">Almeida J</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: almeida.juliana@usp.br.<br /><searchLink fieldCode="AU" term="%22Faria-E-Silva+AL%22">Faria-E-Silva AL</searchLink>; Department of Dentistry, Dental School, Laval University, Québec QC, Canada. Electronic address: andre-luis.faria-e-silva@fmd.ulaval.ca.<br /><searchLink fieldCode="AU" term="%22Lopes-Olhê+FC%22">Lopes-Olhê FC</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: fabiane.lopes@usp.br.<br /><searchLink fieldCode="AU" term="%22Souza-Gabriel+AE%22">Souza-Gabriel AE</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: aline.gabriel@forp.usp.br.<br /><searchLink fieldCode="AU" term="%22Sousa-Neto+MD%22">Sousa-Neto MD</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: sousanet@forp.usp.br.<br /><searchLink fieldCode="AU" term="%22Candemil+AP%22">Candemil AP</searchLink>; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Brazil. Electronic address: amandacandemil@usp.br.
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  Data: <searchLink fieldCode="JN" term="%22101226123%22">Photodiagnosis and photodynamic therapy</searchLink> [Photodiagnosis Photodyn Ther] 2026 Jun; Vol. 59, pp. 105472. <i>Date of Electronic Publication: </i>2026 Apr 17.
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  Data: Journal Article; Systematic Review; Meta-Analysis; Review
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101226123 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-1597 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215721000%22">15721000 </searchLink><i>NLM ISO Abbreviation: </i>Photodiagnosis Photodyn Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.pdpdt.2026.105472
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        Text: English
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              Text: 2026 Jun
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              Y: 2026
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