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Discovery of novel SSRIs for a combination-treatment with pimavanserin.

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Title: Discovery of novel SSRIs for a combination-treatment with pimavanserin.
Authors: Kers A; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden. Electronic address: annika.kers@rgdiscovery.com., Gabos B; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Borhade S; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Andersson E; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Andersson H; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Wellmar U; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Jönsson M; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Gummeson S; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Dreisch K; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Rajabi N; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Sköld N; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Ferreira RJ; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden., Azar MR; Behavioral Pharma, 505 Coast Blvd South, Suite 212, La Jolla, CA 92037, United States., Lowe JA 3rd; JL3Pharma LLC, 28 Cove Side Lane, Stonington, CT 06378, United States., Burstein ES; ACADIA Pharmaceuticals Inc., 12830 El Camino Real #400, San Diego, California 92130, United States.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2026 Aug; Vol. 137, pp. 130662. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Discovery of novel SSRIs for a combination-treatment with pimavanserin.
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  Data: <searchLink fieldCode="AU" term="%22Kers+A%22">Kers A</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden. Electronic address: annika.kers@rgdiscovery.com.<br /><searchLink fieldCode="AU" term="%22Gabos+B%22">Gabos B</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Borhade+S%22">Borhade S</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Andersson+E%22">Andersson E</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Andersson+H%22">Andersson H</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Wellmar+U%22">Wellmar U</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jönsson+M%22">Jönsson M</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Gummeson+S%22">Gummeson S</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Dreisch+K%22">Dreisch K</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Rajabi+N%22">Rajabi N</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sköld+N%22">Sköld N</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Ferreira+RJ%22">Ferreira RJ</searchLink>; RG Discovery AB, Medicon Village, SE-223 63 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Azar+MR%22">Azar MR</searchLink>; Behavioral Pharma, 505 Coast Blvd South, Suite 212, La Jolla, CA 92037, United States.<br /><searchLink fieldCode="AU" term="%22Lowe+JA+3rd%22">Lowe JA 3rd</searchLink>; JL3Pharma LLC, 28 Cove Side Lane, Stonington, CT 06378, United States.<br /><searchLink fieldCode="AU" term="%22Burstein+ES%22">Burstein ES</searchLink>; ACADIA Pharmaceuticals Inc., 12830 El Camino Real #400, San Diego, California 92130, United States.
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2026 Aug; Vol. 137, pp. 130662. <i>Date of Electronic Publication: </i>2026 Apr 17.
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              Text: 2026 Aug
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