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CRISPRi-mediated in vivo gene silencing: a tool for prioritizing drug targets in Mycobacterium abscessus.

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Title: CRISPRi-mediated in vivo gene silencing: a tool for prioritizing drug targets in Mycobacterium abscessus.
Authors: Gupta R; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA., Simcox BS; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA., Rohde KH; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Jun 03; Vol. 70 (6), pp. e0188925. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPRi-mediated in vivo gene silencing: a tool for prioritizing drug targets in Mycobacterium abscessus.
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  Data: <searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Simcox+BS%22">Simcox BS</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Rohde+KH%22">Rohde KH</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2026 Jun 03; Vol. 70 (6), pp. e0188925. <i>Date of Electronic Publication: </i>2026 Apr 20.
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        Value: 10.1128/aac.01889-25
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      – Code: eng
        Text: English
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      – TitleFull: CRISPRi-mediated in vivo gene silencing: a tool for prioritizing drug targets in Mycobacterium abscessus.
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            – D: 03
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              Text: 2026 Jun 03
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              Y: 2026
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