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Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study.

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Title: Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study.
Authors: Kovács J; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary., Köllő Z; Department of Laboratory Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Karvaly BG; Department of Laboratory Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Obeidat M; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary., Nagy R; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Heim Pál National Pediatric Institute, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary., Hegyi P; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Teutsch B; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Department of Radiology, Medical Imaging Centre, Semmelweis University, Budapest, Hungary., Tuboly E; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Wolfson Childhood Cancer Research Centre, Newcastle Centre for Cancer, Newcastle University, Newcastle Upon Tyne, UK., Garami M; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary.
Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2026 Jul; Vol. 73 (7), pp. e70318. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE
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  Data: Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study.
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  Data: <searchLink fieldCode="AU" term="%22Kovács+J%22">Kovács J</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Köllő+Z%22">Köllő Z</searchLink>; Department of Laboratory Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Karvaly+BG%22">Karvaly BG</searchLink>; Department of Laboratory Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Obeidat+M%22">Obeidat M</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Nagy+R%22">Nagy R</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Heim Pál National Pediatric Institute, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.<br /><searchLink fieldCode="AU" term="%22Hegyi+P%22">Hegyi P</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Teutsch+B%22">Teutsch B</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Department of Radiology, Medical Imaging Centre, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Tuboly+E%22">Tuboly E</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Wolfson Childhood Cancer Research Centre, Newcastle Centre for Cancer, Newcastle University, Newcastle Upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Garami+M%22">Garami M</searchLink>; Centre For Translational Medicine, Semmelweis University, Budapest, Hungary.; Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary.
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  Data: <searchLink fieldCode="JN" term="%22101186624%22">Pediatric blood & cancer</searchLink> [Pediatr Blood Cancer] 2026 Jul; Vol. 73 (7), pp. e70318. <i>Date of Electronic Publication: </i>2026 Apr 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley%22">John Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101186624 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-5017 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215455009%22">15455009 </searchLink><i>NLM ISO Abbreviation: </i>Pediatr Blood Cancer <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2026 Jul
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