Histological fidelity and microenvironmental kinome signatures of metastatic patient-derived organoids.

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Title: Histological fidelity and microenvironmental kinome signatures of metastatic patient-derived organoids.
Authors: Leitão-Castro J; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Lopresti AM; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Zornhagen KW; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Albrechtsen R; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Camacho-Roda J; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Ravn MB; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Martinez AG; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Perez LA; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark., Santoni-Rugiu E; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Højgaard M; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Rohrberg KS; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Lassen U; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Erler JT; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.
Source: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2026 Apr 02; Vol. 14, pp. 1735980. Date of Electronic Publication: 2026 Apr 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101632513 Publication Model: eCollection Cited Medium: Print ISSN: 2296-4185 (Print) Linking ISSN: 22964185 NLM ISO Abbreviation: Front Bioeng Biotechnol Subsets: PubMed not MEDLINE
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  Data: Histological fidelity and microenvironmental kinome signatures of metastatic patient-derived organoids.
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  Data: <searchLink fieldCode="AU" term="%22Leitão-Castro+J%22">Leitão-Castro J</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lopresti+AM%22">Lopresti AM</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Zornhagen+KW%22">Zornhagen KW</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Albrechtsen+R%22">Albrechtsen R</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Camacho-Roda+J%22">Camacho-Roda J</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ravn+MB%22">Ravn MB</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Martinez+AG%22">Martinez AG</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Perez+LA%22">Perez LA</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Santoni-Rugiu+E%22">Santoni-Rugiu E</searchLink>; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Højgaard+M%22">Højgaard M</searchLink>; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rohrberg+KS%22">Rohrberg KS</searchLink>; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lassen+U%22">Lassen U</searchLink>; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Erler+JT%22">Erler JT</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101632513%22">Frontiers in bioengineering and biotechnology</searchLink> [Front Bioeng Biotechnol] 2026 Apr 02; Vol. 14, pp. 1735980. <i>Date of Electronic Publication: </i>2026 Apr 02 (<i>Print Publication: </i>2026).
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