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Challenges in early detection and prognostication of sepsis: new approaches from the emergency department and intensive care unit.

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Title: Challenges in early detection and prognostication of sepsis: new approaches from the emergency department and intensive care unit.
Authors: Lafon T; Emergency Department, CHU Limoges, Limoges, France.; Inserm CIC 1435, CHU Limoges, Limoges, France., Weingart M; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Vaidie J; Inserm CIC 1435, CHU Limoges, Limoges, France.; Medical-Surgical Intensive Care Unit, CHU Limoges, Limoges, France., Calfee CS; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Jacob ST; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Walimu Kampala, Uganda., Freund Y; Sorbonne Université, IMProving Emergency Care FHU, Paris, France.; Emergency Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Barraud O; Inserm CIC 1435, CHU Limoges, Limoges, France.; Limoges University, INSERM, CHU Limoges, UMR 1092, Limoges, France., Monneret G; Immunology Laboratory, Edouard Herriot Hospital - Hospices Civils de Lyon, Lyon, France.; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, Claude Bernard Lyon 1 University, Lyon, France., van der Poll T; Center of Infection and Molecular Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Fromage Y; Inserm CIC 1435, CHU Limoges, Limoges, France., François B; Inserm CIC 1435, CHU Limoges, Limoges, France.; Medical-Surgical Intensive Care Unit, CHU Limoges, Limoges, France.; Limoges University, INSERM, CHU Limoges, UMR 1092, Limoges, France.
Source: EClinicalMedicine [EClinicalMedicine] 2026 Apr 06; Vol. 94, pp. 103864. Date of Electronic Publication: 2026 Apr 06 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: The Lancet Country of Publication: England NLM ID: 101733727 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5370 (Electronic) Linking ISSN: 25895370 NLM ISO Abbreviation: EClinicalMedicine Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lafon+T%22">Lafon T</searchLink>; Emergency Department, CHU Limoges, Limoges, France.; Inserm CIC 1435, CHU Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Weingart+M%22">Weingart M</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vaidie+J%22">Vaidie J</searchLink>; Inserm CIC 1435, CHU Limoges, Limoges, France.; Medical-Surgical Intensive Care Unit, CHU Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Calfee+CS%22">Calfee CS</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jacob+ST%22">Jacob ST</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Walimu Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Freund+Y%22">Freund Y</searchLink>; Sorbonne Université, IMProving Emergency Care FHU, Paris, France.; Emergency Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Shapiro+NI%22">Shapiro NI</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Barraud+O%22">Barraud O</searchLink>; Inserm CIC 1435, CHU Limoges, Limoges, France.; Limoges University, INSERM, CHU Limoges, UMR 1092, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Monneret+G%22">Monneret G</searchLink>; Immunology Laboratory, Edouard Herriot Hospital - Hospices Civils de Lyon, Lyon, France.; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, Claude Bernard Lyon 1 University, Lyon, France.<br /><searchLink fieldCode="AU" term="%22van+der+Poll+T%22">van der Poll T</searchLink>; Center of Infection and Molecular Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Fromage+Y%22">Fromage Y</searchLink>; Inserm CIC 1435, CHU Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22François+B%22">François B</searchLink>; Inserm CIC 1435, CHU Limoges, Limoges, France.; Medical-Surgical Intensive Care Unit, CHU Limoges, Limoges, France.; Limoges University, INSERM, CHU Limoges, UMR 1092, Limoges, France.
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  Data: <searchLink fieldCode="JN" term="%22101733727%22">EClinicalMedicine</searchLink> [EClinicalMedicine] 2026 Apr 06; Vol. 94, pp. 103864. <i>Date of Electronic Publication: </i>2026 Apr 06 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22The+Lancet%22">The Lancet </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101733727 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-5370 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225895370%22">25895370 </searchLink><i>NLM ISO Abbreviation: </i>EClinicalMedicine <i>Subsets: </i>PubMed not MEDLINE
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