Intranasally delivered fucoidan nanozyme-decorated photosynthetic Chlamydomonas regulates vascular pathology and hypoxia in diabetes-associated retinal microvascular dysfunction.

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Title: Intranasally delivered fucoidan nanozyme-decorated photosynthetic Chlamydomonas regulates vascular pathology and hypoxia in diabetes-associated retinal microvascular dysfunction.
Authors: Chuang AE; Graduate Institute of Biomedical Materials and Tissue Engineering, International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, New Taipei City, 235603, Taiwan.; Cell Physiology and Molecular Image Research Center, Taipei Medical University, Wan Fang Hospital, Taipei, 11696, Taiwan.; Precision Medicine and Translational Cancer Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan., Chen YL; Graduate Institute of Biomedical Materials and Tissue Engineering, International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, New Taipei City, 235603, Taiwan., Liu CH; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 11031, Taiwan.; Taipei Medical University Research Center of Urology and Kidney, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 11031, Taiwan.; Department of Urology, Shuang Ho Hospital, Taipei Medical University, 291 Zhongzheng Road, Zhonghe District, New Taipei City, 23561, Taiwan., Nguyen HT; Department of Orthopedics and Trauma, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam., Wang TJ; Department of Ophthalmology, Taipei Medical University Hospital, Taipei, 11031, Taiwan.; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan., Lin IC; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Ophthalmology, Wan Fang Hospital, Taipei Medical University, Taipei, 11031, Taiwan.
Source: Materials today. Bio [Mater Today Bio] 2026 Mar 26; Vol. 38, pp. 103060. Date of Electronic Publication: 2026 Mar 26 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101757228 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-0064 (Electronic) Linking ISSN: 25900064 NLM ISO Abbreviation: Mater Today Bio Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Intranasally delivered fucoidan nanozyme-decorated photosynthetic Chlamydomonas regulates vascular pathology and hypoxia in diabetes-associated retinal microvascular dysfunction.
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  Data: <searchLink fieldCode="AU" term="%22Chuang+AE%22">Chuang AE</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, New Taipei City, 235603, Taiwan.; Cell Physiology and Molecular Image Research Center, Taipei Medical University, Wan Fang Hospital, Taipei, 11696, Taiwan.; Precision Medicine and Translational Cancer Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YL%22">Chen YL</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, New Taipei City, 235603, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+CH%22">Liu CH</searchLink>; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 11031, Taiwan.; Taipei Medical University Research Center of Urology and Kidney, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 11031, Taiwan.; Department of Urology, Shuang Ho Hospital, Taipei Medical University, 291 Zhongzheng Road, Zhonghe District, New Taipei City, 23561, Taiwan.<br /><searchLink fieldCode="AU" term="%22Nguyen+HT%22">Nguyen HT</searchLink>; Department of Orthopedics and Trauma, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Wang+TJ%22">Wang TJ</searchLink>; Department of Ophthalmology, Taipei Medical University Hospital, Taipei, 11031, Taiwan.; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+IC%22">Lin IC</searchLink>; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Ophthalmology, Wan Fang Hospital, Taipei Medical University, Taipei, 11031, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101757228%22">Materials today. Bio</searchLink> [Mater Today Bio] 2026 Mar 26; Vol. 38, pp. 103060. <i>Date of Electronic Publication: </i>2026 Mar 26 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101757228 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2590-0064 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225900064%22">25900064 </searchLink><i>NLM ISO Abbreviation: </i>Mater Today Bio <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.mtbio.2026.103060
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              Text: 2026 Mar 26
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