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Results of a phase 1 trial testing ruxolitinib plus venetoclax in patients with relapsed/refractory acute myeloid leukemia.

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Title: Results of a phase 1 trial testing ruxolitinib plus venetoclax in patients with relapsed/refractory acute myeloid leukemia.
Authors: Borate U; Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH., Tognon CE; Division of Oncological Sciences, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Madanat YF; Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX., Misra S; Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Kaempf A; Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Patel PA; Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX., Davis KL; Division of Hematology, Oncology and Stem Cell Transplant and Regenerative Medicine, Department of Pediatrics, Stanford University, Stanford, CA., Sun J; Department of Statistics, Stanford University, Stanford, CA., Stuani L; Division of Hematology, Oncology and Stem Cell Transplant and Regenerative Medicine, Department of Pediatrics, Stanford University, Stanford, CA., Eisenmann ED; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH., Eide CA; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Kurtz SE; Division of Oncological Sciences, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR.; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Watanabe-Smith K; Division of Oncological Sciences, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Johnson K; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Jager A; Division of Hematology, Oncology and Stem Cell Transplant and Regenerative Medicine, Department of Pediatrics, Stanford University, Stanford, CA., Gullaksen SE; Department of Biomedical Data Sciences, Stanford University, Stanford, CA.; Hematology Section, Department of Medicine, Haukeland University Hospital, Bergen, Norway.; K.G. Jebsen Centre for Myeloid Blood Cancer, Department of Clinical Science, University of Bergen, Bergen, Norway.; Centre of Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Robinson B; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, OR., Vu T; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, OR., Plevritis SK; Centre of Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Baker SD; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH., Minnier J; Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Clement P; Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Avaylon S; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Hayes M; Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Newell LF; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Gandhi AP; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Leonard J; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Hayes-Lattin B; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Vasu S; Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH., Cook RJ; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Meyers G; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Maziarz RT; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Traer E; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Swords R; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Tyner JW; Department of Cell, Developmental and Cancer Biology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Druker BJ; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR., Saultz JN; Division of Hematology and Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, OR.
Source: Blood neoplasia [Blood Neoplasia] 2026 Feb 05; Vol. 3 (2), pp. 100205. Date of Electronic Publication: 2026 Feb 05 (Print Publication: 2026).
Publication Type: Clinical Trial; Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918841988906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-3280 (Electronic) Linking ISSN: 29503280 NLM ISO Abbreviation: Blood Neoplasia Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Results of a phase 1 trial testing ruxolitinib plus venetoclax in patients with relapsed/refractory acute myeloid leukemia.
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  Data: <searchLink fieldCode="JN" term="%229918841988906676%22">Blood neoplasia</searchLink> [Blood Neoplasia] 2026 Feb 05; Vol. 3 (2), pp. 100205. <i>Date of Electronic Publication: </i>2026 Feb 05 (<i>Print Publication: </i>2026).
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