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Diallyl Disulfide Mitigates LPS-Induced Inhibition of Osteogenic Differentiation and Alleviates Inflammatory Bone Loss via PI3K/AKT Signaling Pathway.

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Title: Diallyl Disulfide Mitigates LPS-Induced Inhibition of Osteogenic Differentiation and Alleviates Inflammatory Bone Loss via PI3K/AKT Signaling Pathway.
Authors: Wu J; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Guo D; Department of Emergency, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Du Y; Department of Paediatric Oncology, Haematology, Oncology and Immunology, Heidelberg University, Heidelberg, Germany., Wang Z; Department of Orthopedics, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People's Republic of China., Li S; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Xu H; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Chu X; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Gao X; Department of Emergency, The People's Hospital of Nan'an District, Chongqing, 400060, People's Republic of China., Li L; Department of Stem Cell and Regenerative Medicine, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China., Fei J; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Apr 14; Vol. 20, pp. 590959. Date of Electronic Publication: 2026 Apr 14 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diallyl Disulfide Mitigates LPS-Induced Inhibition of Osteogenic Differentiation and Alleviates Inflammatory Bone Loss via PI3K/AKT Signaling Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Guo+D%22">Guo D</searchLink>; Department of Emergency, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Du+Y%22">Du Y</searchLink>; Department of Paediatric Oncology, Haematology, Oncology and Immunology, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Orthopedics, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chu+X%22">Chu X</searchLink>; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Emergency, The People's Hospital of Nan'an District, Chongqing, 400060, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Stem Cell and Regenerative Medicine, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Fei+J%22">Fei J</searchLink>; War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22101475745%22">Drug design, development and therapy</searchLink> [Drug Des Devel Ther] 2026 Apr 14; Vol. 20, pp. 590959. <i>Date of Electronic Publication: </i>2026 Apr 14 (<i>Print Publication: </i>2026).
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              Text: 2026 Apr 14
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