Higher plasma serine levels are associated with favorable values of metabolic health markers among middle-aged and older adults in The Maastricht Study.

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Title: Higher plasma serine levels are associated with favorable values of metabolic health markers among middle-aged and older adults in The Maastricht Study.
Authors: Olsen T; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway., Elshorbagy A; Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, UK.; Department of Physiology, Faculty of Medicine, University of Alexandria, Mowassat Campus, Alexandria, Egypt., Tore EC; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands., Bastani NE; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway., Stolt E; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway., Blokland GAM; Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands., Stehouwer CDA; Department of Chronic Diseases and Metabolism, KU Leuven, ON1bis Herestraat 49 - Box 902, Louvain, 3000, Belgium., Kooi ME; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands., Jansen JFA; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.; Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.; Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands., Eussen SJPM; Department of Epidemiology, Caridovascular Research Institute Maastricht (CARIM), and Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands., Grootswagers P; Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands., Refsum H; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.; Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, UK., Retterstøl K; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.; The Lipid Clinic, Oslo University Hospital, Oslo, Norway., Vinknes KJ; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway., van Greevenbroek MMJ; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands.; Department of Internal Medicine, Maastricht University, Maastricht, The Netherlands., Nichenametla SN; Animal Science Laboratory, Orentreich Foundation for the Advancement of Science, Cold Spring-On-Hudson, NY, 10516, USA. snichenametla@orentreich.org.
Source: GeroScience [Geroscience] 2026 Apr 20. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
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  Data: Higher plasma serine levels are associated with favorable values of metabolic health markers among middle-aged and older adults in The Maastricht Study.
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  Data: <searchLink fieldCode="AU" term="%22Olsen+T%22">Olsen T</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.<br /><searchLink fieldCode="AU" term="%22Elshorbagy+A%22">Elshorbagy A</searchLink>; Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, UK.; Department of Physiology, Faculty of Medicine, University of Alexandria, Mowassat Campus, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Tore+EC%22">Tore EC</searchLink>; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bastani+NE%22">Bastani NE</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.<br /><searchLink fieldCode="AU" term="%22Stolt+E%22">Stolt E</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.<br /><searchLink fieldCode="AU" term="%22Blokland+GAM%22">Blokland GAM</searchLink>; Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Stehouwer+CDA%22">Stehouwer CDA</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, ON1bis Herestraat 49 - Box 902, Louvain, 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Kooi+ME%22">Kooi ME</searchLink>; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jansen+JFA%22">Jansen JFA</searchLink>; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.; Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.; Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Eussen+SJPM%22">Eussen SJPM</searchLink>; Department of Epidemiology, Caridovascular Research Institute Maastricht (CARIM), and Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Grootswagers+P%22">Grootswagers P</searchLink>; Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Refsum+H%22">Refsum H</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.; Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, UK.<br /><searchLink fieldCode="AU" term="%22Retterstøl+K%22">Retterstøl K</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.; The Lipid Clinic, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Vinknes+KJ%22">Vinknes KJ</searchLink>; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, Oslo, 0317, Norway.<br /><searchLink fieldCode="AU" term="%22van+Greevenbroek+MMJ%22">van Greevenbroek MMJ</searchLink>; Department of Internal Medicine, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands.; Department of Internal Medicine, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nichenametla+SN%22">Nichenametla SN</searchLink>; Animal Science Laboratory, Orentreich Foundation for the Advancement of Science, Cold Spring-On-Hudson, NY, 10516, USA. snichenametla@orentreich.org.
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