Pharmacogenetic strategies to mitigate cisplatin-induced ototoxicity in head and neck cancer: A cost-minimization analysis with the use of GSTP1 c.313A>G genotyping.

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Title: Pharmacogenetic strategies to mitigate cisplatin-induced ototoxicity in head and neck cancer: A cost-minimization analysis with the use of GSTP1 c.313A>G genotyping.
Authors: Macedo LT; Department of Oncology and Radiology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil., Ferrari VE; School of Economics and Business (EcoN), Pontifical Catholic University of Campinas (PUCC), Campinas, Brazil., Dias Costa EF; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil., Lourenço GJ; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil., Calonga L; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil., Castilho AM; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil., Chone CT; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil., Passos Lima CS; Department of Oncology and Radiology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.
Source: PloS one [PLoS One] 2026 Apr 20; Vol. 21 (4), pp. e0345371. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacogenetic strategies to mitigate cisplatin-induced ototoxicity in head and neck cancer: A cost-minimization analysis with the use of GSTP1 c.313A>G genotyping.
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  Data: <searchLink fieldCode="AU" term="%22Macedo+LT%22">Macedo LT</searchLink>; Department of Oncology and Radiology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.<br /><searchLink fieldCode="AU" term="%22Ferrari+VE%22">Ferrari VE</searchLink>; School of Economics and Business (EcoN), Pontifical Catholic University of Campinas (PUCC), Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Dias+Costa+EF%22">Dias Costa EF</searchLink>; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.<br /><searchLink fieldCode="AU" term="%22Lourenço+GJ%22">Lourenço GJ</searchLink>; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.<br /><searchLink fieldCode="AU" term="%22Calonga+L%22">Calonga L</searchLink>; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Castilho+AM%22">Castilho AM</searchLink>; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Chone+CT%22">Chone CT</searchLink>; Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Passos+Lima+CS%22">Passos Lima CS</searchLink>; Department of Oncology and Radiology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.; Laboratory of Cancer Genetics (LAGECA), Faculty of Medical Sciences, University of Campinas (UNICAMP), Brazil.
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              Text: 2026 Apr 20
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