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S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.

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Title: S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.
Authors: Reinkemeier F; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Korte R; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Bakri A; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Wallner C; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Drysch M; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Schmidt SV; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Fueth M; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Puscz F; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Steubing Y; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Levkau B; Institute of Molecular Medicine III, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Lehnhardt M; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany., Behr B; Department of Plastic, Reconstructive and Aesthetic Surgery, EVK Essen, Essen, Germany., Wagner JM; Department of Plastic, Reconstructive and Aesthetic Surgery, EVK Essen, Essen, Germany.
Source: Clinical orthopaedics and related research [Clin Orthop Relat Res] 2026 Aug 01; Vol. 484 (8), pp. 1621-1632. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 0075674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1132 (Electronic) Linking ISSN: 0009921X NLM ISO Abbreviation: Clin Orthop Relat Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.
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  Data: <searchLink fieldCode="AU" term="%22Reinkemeier+F%22">Reinkemeier F</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Korte+R%22">Korte R</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Bakri+A%22">Bakri A</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Wallner+C%22">Wallner C</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Drysch+M%22">Drysch M</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+SV%22">Schmidt SV</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Fueth+M%22">Fueth M</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Puscz+F%22">Puscz F</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Steubing+Y%22">Steubing Y</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Levkau+B%22">Levkau B</searchLink>; Institute of Molecular Medicine III, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Lehnhardt+M%22">Lehnhardt M</searchLink>; Department of Plastic Surgery and Hand Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Behr+B%22">Behr B</searchLink>; Department of Plastic, Reconstructive and Aesthetic Surgery, EVK Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+JM%22">Wagner JM</searchLink>; Department of Plastic, Reconstructive and Aesthetic Surgery, EVK Essen, Essen, Germany.
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  Data: <searchLink fieldCode="JN" term="%220075674%22">Clinical orthopaedics and related research</searchLink> [Clin Orthop Relat Res] 2026 Aug 01; Vol. 484 (8), pp. 1621-1632. <i>Date of Electronic Publication: </i>2026 Apr 08.
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      – TitleFull: S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.
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              Text: 2026 Aug 01
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