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Leptin-driven microglial activation in fibromyalgia: mechanistic insights and therapeutic implications.

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Title: Leptin-driven microglial activation in fibromyalgia: mechanistic insights and therapeutic implications.
Authors: Abdelrheem NM; Postgraduate program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt., Ahmed MAE; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt., Mohamed AF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt., Shalaby HN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: heba.nasr@pharma.cu.edu.eg., El Sayed NS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, Al Ryada University for Science and Technology, Sadat City, Menoufia 16504, Egypt.
Source: International immunopharmacology [Int Immunopharmacol] 2026 Jul 01; Vol. 180, pp. 116657. Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Leptin-driven microglial activation in fibromyalgia: mechanistic insights and therapeutic implications.
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  Data: <searchLink fieldCode="AU" term="%22Abdelrheem+NM%22">Abdelrheem NM</searchLink>; Postgraduate program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+MAE%22">Ahmed MAE</searchLink>; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohamed+AF%22">Mohamed AF</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.<br /><searchLink fieldCode="AU" term="%22Shalaby+HN%22">Shalaby HN</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: heba.nasr@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22El+Sayed+NS%22">El Sayed NS</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, Al Ryada University for Science and Technology, Sadat City, Menoufia 16504, Egypt.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2026 Jul 01; Vol. 180, pp. 116657. <i>Date of Electronic Publication: </i>2026 Apr 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.intimp.2026.116657
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      – TitleFull: Leptin-driven microglial activation in fibromyalgia: mechanistic insights and therapeutic implications.
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              Text: 2026 Jul 01
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