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Hospital in-use evaluation of the physical, chemical and affinity stability of the antibody-drug conjugate trastuzumab deruxtecan (Enhertu®).

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Bibliographic Details
Title: Hospital in-use evaluation of the physical, chemical and affinity stability of the antibody-drug conjugate trastuzumab deruxtecan (Enhertu®).
Authors: Douez E; UPR 4301 CBM, CNRS, NMNS department, University of Tours, F-37200 Tours, France; Pharmacy Department, Tours University Hospital, F-37200, France. Electronic address: emmanuel.douez@univ-tours.fr., Joubert N; UMR 1100, CEPR, Team Proteolytic enzymes and their pharmacological targeting in lung diseases, University of Tours, INSERM, F-37032 Tours, France., Gabant G; UPR 4301 CBM, CNRS, MO2VING platform, University of Orleans, 45100 Tours, France., Vidy E; UMR 1100, CEPR, Team Proteolytic enzymes and their pharmacological targeting in lung diseases, University of Tours, INSERM, F-37032 Tours, France., Auvert E; UMR 1100, CEPR, Team Proteolytic enzymes and their pharmacological targeting in lung diseases, University of Tours, INSERM, F-37032 Tours, France., Boursin F; UMR 1282 ISP, Team BioMAP, University of Tours - INRAE, F-37200 Tours, France., Dupeyrol G; UMR 1282 ISP, Team BioMAP, University of Tours - INRAE, F-37200 Tours, France., André V; Pharmacy Department, Tours University Hospital, F-37200, France., Velge Roussel F; UPR 4301 CBM, CNRS, NMNS department, University of Tours, F-37200 Tours, France., Denevault-Sabourin C; UMR 1100, CEPR, Team Proteolytic enzymes and their pharmacological targeting in lung diseases, University of Tours, INSERM, F-37032 Tours, France., Aubrey N; UMR 1282 ISP, Team BioMAP, University of Tours - INRAE, F-37200 Tours, France., Allard-Vannier E; UPR 4301 CBM, CNRS, NMNS department, University of Tours, F-37200 Tours, France.
Source: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2026 Jun 01; Vol. 221, pp. 107536. Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0720
DOI:10.1016/j.ejps.2026.107536