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Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2.

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Title: Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2.
Authors: Nguyen YTK; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Chen F; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Giang E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Saha S; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Ueno LA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Chen C; Southwest National Primate Research Centre (SNPRC) at Texas Biomedical Research Institute, San Antonio, TX, USA.; PKD Foundation, Kansas City, MO, USA., Watson CT; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Tzarum N; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.; Department of Biological Chemistry, Alexander Silberman Institute of Life Sciences, Faculty of Mathematics & Science, The Hebrew University of Jerusalem, Jerusalem, Israel., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. wilson@scripps.edu.; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA. wilson@scripps.edu., Law M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. mlaw@scripps.edu., Stanfield RL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. robyn@scripps.edu.
Source: NPJ vaccines [NPJ Vaccines] 2026 Apr 21. Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines
Database: MEDLINE Ultimate
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  Data: Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+YTK%22">Nguyen YTK</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Giang+E%22">Giang E</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Saha+S%22">Saha S</searchLink>; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Ueno+LA%22">Ueno LA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Southwest National Primate Research Centre (SNPRC) at Texas Biomedical Research Institute, San Antonio, TX, USA.; PKD Foundation, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Watson+CT%22">Watson CT</searchLink>; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Tzarum+N%22">Tzarum N</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.; Department of Biological Chemistry, Alexander Silberman Institute of Life Sciences, Faculty of Mathematics & Science, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Wilson+IA%22">Wilson IA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. wilson@scripps.edu.; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA. wilson@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Law+M%22">Law M</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. mlaw@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Stanfield+RL%22">Stanfield RL</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. robyn@scripps.edu.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2026 Apr 21. <i>Date of Electronic Publication: </i>2026 Apr 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42009696
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              Text: 2026 Apr 21
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