Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial.
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| Title: | Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial. |
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| Authors: | Wang H; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Wang Q; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Liu S; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Department of Medical Genetics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Zhang Y; Department of Hematology, The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an, Huai'an, China., Ding K; University of Toronto Scarborough, Scarborough, ON, Canada., Li X; Soochow Hopes Hematonosis Hospital, Suzhou, China., Jiao W; Department of Hematology, Xian Yang Central Hospital, Xianyang, China., Zhang Q; Soochow Hopes Hematonosis Hospital, Suzhou, China., Fu J; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Cao J; Department of Hematology, Zhangjiagang First People's Hospital, Suzhou, China., Jiao W; Department of Hematology, Hefei First People's Hospital, Hefei, China., Miao M; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Liu Z; Department of Hematology, People Hospital of Xinghua, Xinghua, China., Liu Q; Department of Hematology, Pingxiang Municipal People's Hospital of Jiangxi Province, Pingxiang, China., Yang G; Department of Hematology, Changshu Hospital Affiliated to Soochow University, Changshu NO.1 People's Hospital, Changshu, China., Ma X; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Chen F; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Wang J; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Yan L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Shangguan X; Department of Hematology, Longyan First Hospital, Affiliated to Fujian Medical University, Longyan, China., Xu J; Department of Hematology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China., Lei M; Department of Hematology, Haikou Municipal People's Hospital, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China., Ma H; Department of Hematology, The Third People's Hospital of Zhengzhou, Zhengzhou, China., Zhang L; Department of Hematology, The Second Hospital of Lanzhou University, Lanzhou, China., Liu L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. liminliu2006@163.com., Wu D; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. wudepei@suda.edu.cn. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Apr 21; Vol. 11 (1). Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article; Multicenter Study; Clinical Trial |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02635-2 |
