View in EDS HTML Full Text PDF Full Text

Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial.

Saved in:
Bibliographic Details
Title: Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial.
Authors: Wang H; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Wang Q; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Liu S; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Department of Medical Genetics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Zhang Y; Department of Hematology, The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an, Huai'an, China., Ding K; University of Toronto Scarborough, Scarborough, ON, Canada., Li X; Soochow Hopes Hematonosis Hospital, Suzhou, China., Jiao W; Department of Hematology, Xian Yang Central Hospital, Xianyang, China., Zhang Q; Soochow Hopes Hematonosis Hospital, Suzhou, China., Fu J; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Cao J; Department of Hematology, Zhangjiagang First People's Hospital, Suzhou, China., Jiao W; Department of Hematology, Hefei First People's Hospital, Hefei, China., Miao M; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Liu Z; Department of Hematology, People Hospital of Xinghua, Xinghua, China., Liu Q; Department of Hematology, Pingxiang Municipal People's Hospital of Jiangxi Province, Pingxiang, China., Yang G; Department of Hematology, Changshu Hospital Affiliated to Soochow University, Changshu NO.1 People's Hospital, Changshu, China., Ma X; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Chen F; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Wang J; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Yan L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China., Shangguan X; Department of Hematology, Longyan First Hospital, Affiliated to Fujian Medical University, Longyan, China., Xu J; Department of Hematology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China., Lei M; Department of Hematology, Haikou Municipal People's Hospital, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China., Ma H; Department of Hematology, The Third People's Hospital of Zhengzhou, Zhengzhou, China., Zhang L; Department of Hematology, The Second Hospital of Lanzhou University, Lanzhou, China., Liu L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. liminliu2006@163.com., Wu D; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. wudepei@suda.edu.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Apr 21; Vol. 11 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article; Multicenter Study; Clinical Trial
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42010264
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Department of Medical Genetics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Hematology, The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an, Huai'an, China.<br /><searchLink fieldCode="AU" term="%22Ding+K%22">Ding K</searchLink>; University of Toronto Scarborough, Scarborough, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Soochow Hopes Hematonosis Hospital, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiao+W%22">Jiao W</searchLink>; Department of Hematology, Xian Yang Central Hospital, Xianyang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Soochow Hopes Hematonosis Hospital, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Fu+J%22">Fu J</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Cao+J%22">Cao J</searchLink>; Department of Hematology, Zhangjiagang First People's Hospital, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiao+W%22">Jiao W</searchLink>; Department of Hematology, Hefei First People's Hospital, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Miao+M%22">Miao M</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Hematology, People Hospital of Xinghua, Xinghua, China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; Department of Hematology, Pingxiang Municipal People's Hospital of Jiangxi Province, Pingxiang, China.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; Department of Hematology, Changshu Hospital Affiliated to Soochow University, Changshu NO.1 People's Hospital, Changshu, China.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Shangguan+X%22">Shangguan X</searchLink>; Department of Hematology, Longyan First Hospital, Affiliated to Fujian Medical University, Longyan, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Hematology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.<br /><searchLink fieldCode="AU" term="%22Lei+M%22">Lei M</searchLink>; Department of Hematology, Haikou Municipal People's Hospital, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Ma+H%22">Ma H</searchLink>; Department of Hematology, The Third People's Hospital of Zhengzhou, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Hematology, The Second Hospital of Lanzhou University, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. liminliu2006@163.com.<br /><searchLink fieldCode="AU" term="%22Wu+D%22">Wu D</searchLink>; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Collaborative Innovation Center of Hematology, Suzhou, China. wudepei@suda.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101676423%22">Signal transduction and targeted therapy</searchLink> [Signal Transduct Target Ther] 2026 Apr 21; Vol. 11 (1). <i>Date of Electronic Publication: </i>2026 Apr 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Multicenter Study; Clinical Trial
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42010264
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41392-026-02635-2
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Sirolimus plus roxadustat synergistically enhances immunosuppression and erythropoiesis in pure red cell aplasia: a multicenter trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wang H
      – PersonEntity:
          Name:
            NameFull: Wang Q
      – PersonEntity:
          Name:
            NameFull: Liu S
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Ding K
      – PersonEntity:
          Name:
            NameFull: Li X
      – PersonEntity:
          Name:
            NameFull: Jiao W
      – PersonEntity:
          Name:
            NameFull: Zhang Q
      – PersonEntity:
          Name:
            NameFull: Fu J
      – PersonEntity:
          Name:
            NameFull: Cao J
      – PersonEntity:
          Name:
            NameFull: Jiao W
      – PersonEntity:
          Name:
            NameFull: Miao M
      – PersonEntity:
          Name:
            NameFull: Liu Z
      – PersonEntity:
          Name:
            NameFull: Liu Q
      – PersonEntity:
          Name:
            NameFull: Yang G
      – PersonEntity:
          Name:
            NameFull: Ma X
      – PersonEntity:
          Name:
            NameFull: Chen F
      – PersonEntity:
          Name:
            NameFull: Wang J
      – PersonEntity:
          Name:
            NameFull: Yan L
      – PersonEntity:
          Name:
            NameFull: Shangguan X
      – PersonEntity:
          Name:
            NameFull: Xu J
      – PersonEntity:
          Name:
            NameFull: Lei M
      – PersonEntity:
          Name:
            NameFull: Ma H
      – PersonEntity:
          Name:
            NameFull: Zhang L
      – PersonEntity:
          Name:
            NameFull: Liu L
      – PersonEntity:
          Name:
            NameFull: Wu D
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 04
              Text: 2026 Apr 21
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2059-3635
          Numbering:
            – Type: volume
              Value: 11
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Signal transduction and targeted therapy
              Type: main
ResultId 1