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Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation.

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Title: Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation.
Authors: Huang YN; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Tsou MY; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan., Li PH; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Chen JC; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Chen SC; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan., Hsieh HI; School of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Education, National Taiwan University Hospital, Taipei, Taiwan., Meyerowitz-Katz G; School of Health and Society, University of Wollongong, Wollongong, Australia., Liu YL; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan.; Master Program for Biomedical Engineering, China Medical University, Taichung, Taiwan., Su PH; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jul; Vol. 28 (7), pp. 5834-5847. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation.
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  Data: <searchLink fieldCode="AU" term="%22Huang+YN%22">Huang YN</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsou+MY%22">Tsou MY</searchLink>; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+PH%22">Li PH</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+JC%22">Chen JC</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+SC%22">Chen SC</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+HI%22">Hsieh HI</searchLink>; School of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Education, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Meyerowitz-Katz+G%22">Meyerowitz-Katz G</searchLink>; School of Health and Society, University of Wollongong, Wollongong, Australia.<br /><searchLink fieldCode="AU" term="%22Liu+YL%22">Liu YL</searchLink>; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan.; Master Program for Biomedical Engineering, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+PH%22">Su PH</searchLink>; Division of Genetics and Endocrinology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22100883645%22">Diabetes, obesity & metabolism</searchLink> [Diabetes Obes Metab] 2026 Jul; Vol. 28 (7), pp. 5834-5847. <i>Date of Electronic Publication: </i>2026 Apr 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100883645 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1463-1326 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214628902%22">14628902 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Obes Metab <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1111/dom.70786
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      – Code: eng
        Text: English
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        StartPage: 5834
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      – TitleFull: Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation.
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            NameFull: Tsou MY
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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              Value: 1463-1326
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              Value: 28
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              Value: 7
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            – TitleFull: Diabetes, obesity & metabolism
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