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Deficiency of GCN5 exacerbates pulmonary fibrosis by disrupting the LKB1-AMPK pathway.

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Title: Deficiency of GCN5 exacerbates pulmonary fibrosis by disrupting the LKB1-AMPK pathway.
Authors: Byun S; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea., Kim H; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea., Lee SH; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea., Kwon JH; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea., Kim H; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea., Sohn MH; Department of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Yonsei University College of Medicine, Seoul, Korea., Shim HS; Department of Pathology, Yonsei University College of Medicine, Seoul, Korea., Park MS; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea., Lee CG; Hanyang University, Intercollege, Seoul, Korea.; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Elias JA; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Yoo JY; Department of Biomedical Laboratory Science, Yonsei University MIRAE Campus, Wonju, Korea., Park SY; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea. SOOYEONP@yuhs.ac., Yoon HG; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 120-752, Korea. YHGEUN@yuhs.ac.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2026 Apr 20; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1478-811X
DOI:10.1186/s12964-026-02757-8