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Enantioselective Pharmacokinetics of Venlafaxine in the Presence of CYP2D6 Inhibition: A Population Parent-Metabolite Modeling Approach.

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Title: Enantioselective Pharmacokinetics of Venlafaxine in the Presence of CYP2D6 Inhibition: A Population Parent-Metabolite Modeling Approach.
Authors: Alves BCM; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil., Yamamoto PA; Department of Pharmaceutics, Center for Pharmacometrics & Systems Pharmacology, University of Florida, Orlando, FL, USA., Souza CDS; School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil., Lanchote VL; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirão Preto, Brazil., Rocha A; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirão Preto, Brazil., de Moraes NV; Department of Pharmaceutics, Center for Pharmacometrics & Systems Pharmacology, University of Florida, Orlando, FL, USA., Godoy ALPC; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Source: Journal of clinical pharmacology [J Clin Pharmacol] 2026 Apr; Vol. 66 (4), pp. e70194.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Enantioselective Pharmacokinetics of Venlafaxine in the Presence of CYP2D6 Inhibition: A Population Parent-Metabolite Modeling Approach.
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  Data: <searchLink fieldCode="AU" term="%22Alves+BCM%22">Alves BCM</searchLink>; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.<br /><searchLink fieldCode="AU" term="%22Yamamoto+PA%22">Yamamoto PA</searchLink>; Department of Pharmaceutics, Center for Pharmacometrics & Systems Pharmacology, University of Florida, Orlando, FL, USA.<br /><searchLink fieldCode="AU" term="%22Souza+CDS%22">Souza CDS</searchLink>; School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Lanchote+VL%22">Lanchote VL</searchLink>; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirão Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+A%22">Rocha A</searchLink>; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirão Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Moraes+NV%22">de Moraes NV</searchLink>; Department of Pharmaceutics, Center for Pharmacometrics & Systems Pharmacology, University of Florida, Orlando, FL, USA.<br /><searchLink fieldCode="AU" term="%22Godoy+ALPC%22">Godoy ALPC</searchLink>; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
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  Data: <searchLink fieldCode="JN" term="%220366372%22">Journal of clinical pharmacology</searchLink> [J Clin Pharmacol] 2026 Apr; Vol. 66 (4), pp. e70194.
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        Value: 10.1002/jcph.70194
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              Text: 2026 Apr
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