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Protocol for enhancing CRISPR-Cas9 genome editing using histone deacetylase inhibition and engineered virus-like particle delivery.

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Title: Protocol for enhancing CRISPR-Cas9 genome editing using histone deacetylase inhibition and engineered virus-like particle delivery.
Authors: Djamshidi M; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Tanida R; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Heshmatzad K; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Krowicki H; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Hill A; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada., Yang Y; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Riabowol K; Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Departments of Oncology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address: karl@ucalgary.ca.
Source: STAR protocols [STAR Protoc] 2026 Jun 19; Vol. 7 (2), pp. 104493. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE
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