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BmooMPα-I ameliorates aortic fibrosis and hypertrophy in 2K1C hypertensive rats by reducing matrix metalloproteinase-2 activity.

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Title: BmooMPα-I ameliorates aortic fibrosis and hypertrophy in 2K1C hypertensive rats by reducing matrix metalloproteinase-2 activity.
Authors: Dias WF; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil., Chang Estrada JE; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil; Institute of Chemical, Biological, Biomedical and Biophysical Research, Mariano Gálvez University of Guatemala, Guatemala., Silva SCP; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil., Gonçalves PR; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil., Maciel Lima A; Laboratory of Biotechnology and Applied Health Education, Oswaldo Cruz Foundation, Rondônia Unit, Porto Velho, RO, 76812-245, Brazil., Hamoy M; Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil., Zingali RB; Universidade Federal do Rio de Janeiro , Instituto de Bioquimica Medica Leopoldo de Meis, Lab. Hemostase e Venenos, Rio de Janeiro, RJ, 21941-902, Brazil., Martins Soares A; São Lucas University Center and National Institute of Science and Technology of Epidemiology of the Western Amazon, Porto Velho, RO, 76805-846, Brazil; Laboratory of Protein Biotechnology and Education Applied to One Health (LABIOPROT), National Institute of Science and Technology for Research and Knowledge of Excellence in Western/Eastern Amazonia (INCT CONEXAO), Oswaldo Cruz Foundation (FIOCRUZ), Federal University of Rondônia (UNIR), Porto Velho, RO, 76812-245, Brazil., Chagas Monteiro M; Laboratory of Immunology, Microbiology and In Vitro Assays, National Institute of Science and Technology for Pharmaceutical Innovation in the Amazon, Faculty of Pharmacy, Federal University of Para, Belem, PA, 66075-110, Brazil., Gerlach RF; Department of Basic and Oral Biology, Faculty of Dentistry of Ribeirao Preto, University of São Paulo (FORP/USP), Ribeirao Preto, SP, 14040-904, Brazil., Rodrigues KE; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil., Prado AF; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil. Electronic address: alejandrofp@ufpa.br.
Source: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2026 Aug 01; Vol. 278, pp. 109120. Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 1307333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3150 (Electronic) Linking ISSN: 00410101 NLM ISO Abbreviation: Toxicon Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: BmooMPα-I ameliorates aortic fibrosis and hypertrophy in 2K1C hypertensive rats by reducing matrix metalloproteinase-2 activity.
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  Data: <searchLink fieldCode="AU" term="%22Dias+WF%22">Dias WF</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Chang+Estrada+JE%22">Chang Estrada JE</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil; Institute of Chemical, Biological, Biomedical and Biophysical Research, Mariano Gálvez University of Guatemala, Guatemala.<br /><searchLink fieldCode="AU" term="%22Silva+SCP%22">Silva SCP</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Gonçalves+PR%22">Gonçalves PR</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Maciel+Lima+A%22">Maciel Lima A</searchLink>; Laboratory of Biotechnology and Applied Health Education, Oswaldo Cruz Foundation, Rondônia Unit, Porto Velho, RO, 76812-245, Brazil.<br /><searchLink fieldCode="AU" term="%22Hamoy+M%22">Hamoy M</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Zingali+RB%22">Zingali RB</searchLink>; Universidade Federal do Rio de Janeiro , Instituto de Bioquimica Medica Leopoldo de Meis, Lab. Hemostase e Venenos, Rio de Janeiro, RJ, 21941-902, Brazil.<br /><searchLink fieldCode="AU" term="%22Martins+Soares+A%22">Martins Soares A</searchLink>; São Lucas University Center and National Institute of Science and Technology of Epidemiology of the Western Amazon, Porto Velho, RO, 76805-846, Brazil; Laboratory of Protein Biotechnology and Education Applied to One Health (LABIOPROT), National Institute of Science and Technology for Research and Knowledge of Excellence in Western/Eastern Amazonia (INCT CONEXAO), Oswaldo Cruz Foundation (FIOCRUZ), Federal University of Rondônia (UNIR), Porto Velho, RO, 76812-245, Brazil.<br /><searchLink fieldCode="AU" term="%22Chagas+Monteiro+M%22">Chagas Monteiro M</searchLink>; Laboratory of Immunology, Microbiology and In Vitro Assays, National Institute of Science and Technology for Pharmaceutical Innovation in the Amazon, Faculty of Pharmacy, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Gerlach+RF%22">Gerlach RF</searchLink>; Department of Basic and Oral Biology, Faculty of Dentistry of Ribeirao Preto, University of São Paulo (FORP/USP), Ribeirao Preto, SP, 14040-904, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+KE%22">Rodrigues KE</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Prado+AF%22">Prado AF</searchLink>; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Para, Belem, PA, 66075-110, Brazil. Electronic address: alejandrofp@ufpa.br.
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  Data: <searchLink fieldCode="JN" term="%221307333%22">Toxicon : official journal of the International Society on Toxinology</searchLink> [Toxicon] 2026 Aug 01; Vol. 278, pp. 109120. <i>Date of Electronic Publication: </i>2026 Apr 19.
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