GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy.
Saved in:
| Title: | GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy. |
|---|---|
| Authors: | Timsina J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Jiang C; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK., Tao F; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA., Dalmasso MC; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Estudios en Neurociencias y Sistemas Complejos (ENyS), CONICET-HEC-UNAJ, Buenos Aires, Argentina., Najar J; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Anastasi F; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain., Ohlei O; Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, Lübeck, Germany., Puerta Fuentes R; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Yang C; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Bradley J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Western D; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Ali M; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Wang C; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Yang C; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Wu Y; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA., Liu M; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Budde J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Williams J; UK Dementia Research Institute at Cardiff, Cardiff, UK., Mahoney R; UK Dementia Research Institute at Cardiff, Cardiff, UK., Castillo Morales A; UK Dementia Research Institute at Cardiff, Cardiff, UK., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Dumitrescu L; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Wang TC; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Tesi N; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., Kern S; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Department of Neuropsychiatry, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., Waern M; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden., Skoog I; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Department of Neuropsychiatry, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., van Harten A; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Pijnenburg YAL; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., van der Flier WM; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Sánchez-Juan P; Reina Sofia Alzheimer Center, CIEN Foundation, ISCIII, Madrid, Spain., Rodriguez-Rodriguez E; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Neurology Service, Marqués de Valdecilla University Hospital, Santander, Spain., Kleineidam L; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Berlin, Germany., Schneider A; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Küçükali F; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Bellenguez C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France., Grenier-Boley B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France., Heikkinen S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., de Rojas I; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Rujescu D; Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany., Scherbaum N; LVR-University Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, Essen, Germany., Hausner L; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Grimmer T; Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, TUM School of Medicine and Health, Munich, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Medical Science Department, iBiMED, Aveiro, Portugal., Vandenberghe R; Department of Neurology, UZ Leuven, Leuven, Belgium., Engelborghs S; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neurology, Universitair Ziekenhuis Brussel and Neuroprotection and Neuromodulation (NEUR) Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium., Heilmann-Heimbach S; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Schmid M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany., Tegos T; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Greece., Scarmeas N; 1st Department of Neurology, Aiginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.; Depatment of Neurology, Columbia University, New York, NY, USA., Dols-Icardo O; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain., Moreno F; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain.; Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain., Pérez-Tur J; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain., Bullido MJ; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain.; Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.; Universidad Autónoma de Madrid, Madrid, Spain., Sánchez-Valle R; Alzheimer's disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain., Álvarez V; Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Av. del Hospital Universitario, Asturias, Spain., García-González P; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Mir P; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain., Real LM; Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain., Piñol-Ripoll G; Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain., García-Alberca JM; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain.; Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain., Seelaar H; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Ramakers I; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands., Papma J; Neurology department Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Internal Medicine Department, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Hulsman M; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar Technical University Munich, Munich, Germany., Perneczky R; German Center for Neurodegenerative Diseases (DZNE Munich), Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, UK., Buerger K; German Center for Neurodegenerative Diseases (DZNE Munich), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Nöthen MM; Institute of Human Genetics; University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Lewczuk P; Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.; Department of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland., Kornhuber J; Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany., Hampel H; Sorbonne University, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l'hôpital, Paris, France., Giegling I; Division of General Psychiatry, Dept. of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Goldhardt O; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Diehl-Schmid J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Andrade V; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany., Heneka MM; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Frölich L; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Vogelgsang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; Department of Psychiatry, Harvard Medical School McLean Hospital, Belmont, MA, USA., Graff C; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden., Thonberg H; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden., Ullgren A; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden., Papenberg G; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Deleuze JF; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, Evry, France., Dufouil C; Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France.; CHU de Bordeaux, Pole santé publique, Bordeaux, France., Wagner M; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Jessen F; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany., Holstege H; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., van Duijn C; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, UK., Lebouvier T; Univ.Lille, Inserm, CHULille, Lille Neuroscience & Cognition, UMR-S1172, Lille, France., Hannon O; Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France., Leinonen V; Department of Neurosurgery, Kuopio University Hospital and Institute of Clinical Medicine-Neurosurgery, University of Eastern Finland, Kuopio, Finland., Soininen H; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Herukka SK; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, NeuroCenter, Kuopio University Hospital, Kuopio, Finland., Giedraitis V; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden., Löwenmark M; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden., Kilander L; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden., Genius P; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain., Rodríguez B; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain., Luckett ES; Department of Radiology and Nuclear Medicine, Amsterdam UMC location VUmc, Amsterdam, Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.; Laboratory for Cognitive Neurology, KU Leuven, Leuven, Belgium.; Laboratory for Complex Genetics, KU Leuven, Leuven, Belgium., Navarro A; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Department of Experimental and Health Sciences, Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, Barcelona, Spain., Cano A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Marquié M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Blennow K; Clinical neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France., Zetterberg H; Clinical neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Lleo A; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain., Boada M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Ruiz A; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases and Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA., Lee VM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Van Deerlin VM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Deming Y; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Johnson SC; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Engelman CD; Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Pastor P; Unit of Neurodegenerative diseases, Department of Neurology, University Hospital Germans Trias i Pujol and The Germans Trias i Pujol Research Institute (IGTP) Badalona, Barcelona, Spain., Alvarez I; Unit of Neurodegenerative diseases, Department of Neurology, University Hospital Germans Trias i Pujol and The Germans Trias i Pujol Research Institute (IGTP) Badalona, Barcelona, Spain., Peskind ER; Veterans Affairs Northwest Mental Illness Research, Education, and Clinical Center, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA., Heslegrave AJ; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Saykin AJ; Indiana Alzheimer's Disease Research Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA., Nho K; Indiana Alzheimer's Disease Research Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., McDade E; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Renton AE; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Goate A; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ibanez L; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Riemenschneider M; Department of Psychiatry, Saarland University, Homburg, Germany., Albert MS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Laws SM; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Porter T; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia., O'Brien EK; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Shaw LM; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases and Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA., Tijms BM; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Ingelsson M; Krembil Brain Institute, University Health Network, Toronto, ON, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Visser PJ; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, VUmc, Amsterdam, the Netherlands.; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands., Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., Sleegers K; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Ritchie CW; Scottish Brain Sciences, Scottish Gas Murrayfield Stadium, Edinburgh, UK.; School of Medicine, University of St Andrews, St Andrews, UK., Sims R; Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., Belloy M; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Lambert JC; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France., Vilor-Tejedor N; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain.; Department of Human Genetics, Radboud University Medical Center, Nijgmegen, the Netherlands., Fernández MV; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Li QS; Neuroscience, Janssen Research & Development LLC, Titusville, NJ, USA.; JRD Data Science, Janssen Research & Development LLC, Titusville, NJ, USA.; CHDI Management Inc., Princeton, NJ, USA., Nagle MW; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK., Ramirez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany., Bertram L; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., van der Lee SJ; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Section Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu. |
| Source: | Nature communications [Nat Commun] 2026 Apr 21. Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42014397 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Timsina+J%22">Timsina J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+C%22">Jiang C</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22McCartney+DL%22">McCartney DL</searchLink>; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tao+F%22">Tao F</searchLink>; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dalmasso+MC%22">Dalmasso MC</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Estudios en Neurociencias y Sistemas Complejos (ENyS), CONICET-HEC-UNAJ, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Najar+J%22">Najar J</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Anastasi+F%22">Anastasi F</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ohlei+O%22">Ohlei O</searchLink>; Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Puerta+Fuentes+R%22">Puerta Fuentes R</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Bradley+J%22">Bradley J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Western+D%22">Western D</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ali+M%22">Ali M</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Budde+J%22">Budde J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Williams+J%22">Williams J</searchLink>; UK Dementia Research Institute at Cardiff, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Mahoney+R%22">Mahoney R</searchLink>; UK Dementia Research Institute at Cardiff, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Castillo+Morales+A%22">Castillo Morales A</searchLink>; UK Dementia Research Institute at Cardiff, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Dumitrescu+L%22">Dumitrescu L</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wang+TC%22">Wang TC</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Tesi+N%22">Tesi N</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kern+S%22">Kern S</searchLink>; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Department of Neuropsychiatry, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Waern+M%22">Waern M</searchLink>; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Skoog+I%22">Skoog I</searchLink>; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Department of Neuropsychiatry, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22van+Harten+A%22">van Harten A</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pijnenburg+YAL%22">Pijnenburg YAL</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Flier+WM%22">van der Flier WM</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sánchez-Juan+P%22">Sánchez-Juan P</searchLink>; Reina Sofia Alzheimer Center, CIEN Foundation, ISCIII, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Rodriguez+E%22">Rodriguez-Rodriguez E</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Neurology Service, Marqués de Valdecilla University Hospital, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Kleineidam+L%22">Kleineidam L</searchLink>; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Küçükali+F%22">Küçükali F</searchLink>; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Bellenguez+C%22">Bellenguez C</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Grenier-Boley+B%22">Grenier-Boley B</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Heikkinen+S%22">Heikkinen S</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22de+Rojas+I%22">de Rojas I</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rujescu+D%22">Rujescu D</searchLink>; Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Scherbaum+N%22">Scherbaum N</searchLink>; LVR-University Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Hausner+L%22">Hausner L</searchLink>; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Grimmer+T%22">Grimmer T</searchLink>; Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, TUM School of Medicine and Health, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Medical Science Department, iBiMED, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Vandenberghe+R%22">Vandenberghe R</searchLink>; Department of Neurology, UZ Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Engelborghs+S%22">Engelborghs S</searchLink>; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neurology, Universitair Ziekenhuis Brussel and Neuroprotection and Neuromodulation (NEUR) Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Heilmann-Heimbach+S%22">Heilmann-Heimbach S</searchLink>; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+M%22">Schmid M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Tegos+T%22">Tegos T</searchLink>; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Scarmeas+N%22">Scarmeas N</searchLink>; 1st Department of Neurology, Aiginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.; Depatment of Neurology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dols-Icardo+O%22">Dols-Icardo O</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Moreno+F%22">Moreno F</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain.; Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Tur+J%22">Pérez-Tur J</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bullido+MJ%22">Bullido MJ</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain.; Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.; Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Valle+R%22">Sánchez-Valle R</searchLink>; Alzheimer's disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+V%22">Álvarez V</searchLink>; Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Av. del Hospital Universitario, Asturias, Spain.<br /><searchLink fieldCode="AU" term="%22García-González+P%22">García-González P</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mir+P%22">Mir P</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Real+LM%22">Real LM</searchLink>; Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Piñol-Ripoll+G%22">Piñol-Ripoll G</searchLink>; Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22García-Alberca+JM%22">García-Alberca JM</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain.; Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Seelaar+H%22">Seelaar H</searchLink>; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ramakers+I%22">Ramakers I</searchLink>; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Papma+J%22">Papma J</searchLink>; Neurology department Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Internal Medicine Department, Erasmus MC University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hulsman+M%22">Hulsman M</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Laske+C%22">Laske C</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Teipel+S%22">Teipel S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Perneczky+R%22">Perneczky R</searchLink>; German Center for Neurodegenerative Diseases (DZNE Munich), Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Buerger+K%22">Buerger K</searchLink>; German Center for Neurodegenerative Diseases (DZNE Munich), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Nöthen+MM%22">Nöthen MM</searchLink>; Institute of Human Genetics; University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Lewczuk+P%22">Lewczuk P</searchLink>; Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.; Department of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland.<br /><searchLink fieldCode="AU" term="%22Kornhuber+J%22">Kornhuber J</searchLink>; Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hampel+H%22">Hampel H</searchLink>; Sorbonne University, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l'hôpital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Giegling+I%22">Giegling I</searchLink>; Division of General Psychiatry, Dept. of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Goldhardt+O%22">Goldhardt O</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Diehl-Schmid+J%22">Diehl-Schmid J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Andrade+V%22">Andrade V</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Heneka+MM%22">Heneka MM</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Frölich+L%22">Frölich L</searchLink>; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Vogelgsang+J%22">Vogelgsang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; Department of Psychiatry, Harvard Medical School McLean Hospital, Belmont, MA, USA.<br /><searchLink fieldCode="AU" term="%22Graff+C%22">Graff C</searchLink>; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Thonberg+H%22">Thonberg H</searchLink>; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ullgren+A%22">Ullgren A</searchLink>; Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden.; Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Papenberg+G%22">Papenberg G</searchLink>; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Deleuze+JF%22">Deleuze JF</searchLink>; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, Evry, France.<br /><searchLink fieldCode="AU" term="%22Dufouil+C%22">Dufouil C</searchLink>; Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France.; CHU de Bordeaux, Pole santé publique, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Holstege+H%22">Holstege H</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22van+Duijn+C%22">van Duijn C</searchLink>; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lebouvier+T%22">Lebouvier T</searchLink>; Univ.Lille, Inserm, CHULille, Lille Neuroscience & Cognition, UMR-S1172, Lille, France.<br /><searchLink fieldCode="AU" term="%22Hannon+O%22">Hannon O</searchLink>; Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France.<br /><searchLink fieldCode="AU" term="%22Leinonen+V%22">Leinonen V</searchLink>; Department of Neurosurgery, Kuopio University Hospital and Institute of Clinical Medicine-Neurosurgery, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Soininen+H%22">Soininen H</searchLink>; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Herukka+SK%22">Herukka SK</searchLink>; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, NeuroCenter, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Löwenmark+M%22">Löwenmark M</searchLink>; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Kilander+L%22">Kilander L</searchLink>; Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Genius+P%22">Genius P</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+B%22">Rodríguez B</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Luckett+ES%22">Luckett ES</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam UMC location VUmc, Amsterdam, Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.; Laboratory for Cognitive Neurology, KU Leuven, Leuven, Belgium.; Laboratory for Complex Genetics, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Navarro+A%22">Navarro A</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Department of Experimental and Health Sciences, Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cano+A%22">Cano A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Marquié+M%22">Marquié M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Clinical neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Clinical neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Lleo+A%22">Lleo A</searchLink>; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Boada+M%22">Boada M</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases and Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lee+VM%22">Lee VM</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Deerlin+VM%22">Van Deerlin VM</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Deming+Y%22">Deming Y</searchLink>; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+SC%22">Johnson SC</searchLink>; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Engelman+CD%22">Engelman CD</searchLink>; Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Pastor+P%22">Pastor P</searchLink>; Unit of Neurodegenerative diseases, Department of Neurology, University Hospital Germans Trias i Pujol and The Germans Trias i Pujol Research Institute (IGTP) Badalona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alvarez+I%22">Alvarez I</searchLink>; Unit of Neurodegenerative diseases, Department of Neurology, University Hospital Germans Trias i Pujol and The Germans Trias i Pujol Research Institute (IGTP) Badalona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Peskind+ER%22">Peskind ER</searchLink>; Veterans Affairs Northwest Mental Illness Research, Education, and Clinical Center, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Heslegrave+AJ%22">Heslegrave AJ</searchLink>; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Saykin+AJ%22">Saykin AJ</searchLink>; Indiana Alzheimer's Disease Research Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Nho+K%22">Nho K</searchLink>; Indiana Alzheimer's Disease Research Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22McDade+E%22">McDade E</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Renton+AE%22">Renton AE</searchLink>; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Goate+A%22">Goate A</searchLink>; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ibanez+L%22">Ibanez L</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Riemenschneider+M%22">Riemenschneider M</searchLink>; Department of Psychiatry, Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Albert+MS%22">Albert MS</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Laws+SM%22">Laws SM</searchLink>; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Porter+T%22">Porter T</searchLink>; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia.<br /><searchLink fieldCode="AU" term="%22O'Brien+EK%22">O'Brien EK</searchLink>; Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Shaw+LM%22">Shaw LM</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases and Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tijms+BM%22">Tijms BM</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ingelsson+M%22">Ingelsson M</searchLink>; Krembil Brain Institute, University Health Network, Toronto, ON, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Visser+PJ%22">Visser PJ</searchLink>; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, VUmc, Amsterdam, the Netherlands.; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hiltunen+M%22">Hiltunen M</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Sleegers+K%22">Sleegers K</searchLink>; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Complex Genetics of Alzheimer's Disease Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Ritchie+CW%22">Ritchie CW</searchLink>; Scottish Brain Sciences, Scottish Gas Murrayfield Stadium, Edinburgh, UK.; School of Medicine, University of St Andrews, St Andrews, UK.<br /><searchLink fieldCode="AU" term="%22Sims+R%22">Sims R</searchLink>; Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Belloy+M%22">Belloy M</searchLink>; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Lambert+JC%22">Lambert JC</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Vilor-Tejedor+N%22">Vilor-Tejedor N</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Hospital del Mar Research Institute, Barcelona, Spain.; Department of Human Genetics, Radboud University Medical Center, Nijgmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Fernández+MV%22">Fernández MV</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Li+QS%22">Li QS</searchLink>; Neuroscience, Janssen Research & Development LLC, Titusville, NJ, USA.; JRD Data Science, Janssen Research & Development LLC, Titusville, NJ, USA.; CHDI Management Inc., Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Nagle+MW%22">Nagle MW</searchLink>; Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Marioni+RE%22">Marioni RE</searchLink>; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ramirez+A%22">Ramirez A</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Bertram+L%22">Bertram L</searchLink>; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22van+der+Lee+SJ%22">van der Lee SJ</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Section Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. cruchagac@wustl.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 21. <i>Date of Electronic Publication: </i>2026 Apr 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42014397 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-026-71682-8 Languages: – Code: eng Text: English Titles: – TitleFull: GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Timsina J – PersonEntity: Name: NameFull: Jiang C – PersonEntity: Name: NameFull: McCartney DL – PersonEntity: Name: NameFull: Tao F – PersonEntity: Name: NameFull: Dalmasso MC – PersonEntity: Name: NameFull: Najar J – PersonEntity: Name: NameFull: Anastasi F – PersonEntity: Name: NameFull: Ohlei O – PersonEntity: Name: NameFull: Puerta Fuentes R – PersonEntity: Name: NameFull: Yang C – PersonEntity: Name: NameFull: Bradley J – PersonEntity: Name: NameFull: Western D – PersonEntity: Name: NameFull: Ali M – PersonEntity: Name: NameFull: Wang C – PersonEntity: Name: NameFull: Yang C – PersonEntity: Name: NameFull: Wu Y – PersonEntity: Name: NameFull: Liu M – PersonEntity: Name: NameFull: Budde J – PersonEntity: Name: NameFull: Williams J – PersonEntity: Name: NameFull: Mahoney R – PersonEntity: Name: NameFull: Castillo Morales A – PersonEntity: Name: NameFull: Hohman TJ – PersonEntity: Name: NameFull: Dumitrescu L – PersonEntity: Name: NameFull: Wang TC – PersonEntity: Name: NameFull: Tesi N – PersonEntity: Name: NameFull: Kern S – PersonEntity: Name: NameFull: Waern M – PersonEntity: Name: NameFull: Skoog I – PersonEntity: Name: NameFull: van Harten A – PersonEntity: Name: NameFull: Pijnenburg YAL – PersonEntity: Name: NameFull: van der Flier WM – PersonEntity: Name: NameFull: Sánchez-Juan P – PersonEntity: Name: NameFull: Rodriguez-Rodriguez E – PersonEntity: Name: NameFull: Kleineidam L – PersonEntity: Name: NameFull: Peters O – PersonEntity: Name: NameFull: Schneider A – PersonEntity: Name: NameFull: Küçükali F – PersonEntity: Name: NameFull: Bellenguez C – PersonEntity: Name: NameFull: Grenier-Boley B – PersonEntity: Name: NameFull: Heikkinen S – PersonEntity: Name: NameFull: de Rojas I – PersonEntity: Name: NameFull: Rujescu D – PersonEntity: Name: NameFull: Scherbaum N – PersonEntity: Name: NameFull: Hausner L – PersonEntity: Name: NameFull: Düzel E – PersonEntity: Name: NameFull: Grimmer T – PersonEntity: Name: NameFull: Wiltfang J – PersonEntity: Name: NameFull: Vandenberghe R – PersonEntity: Name: NameFull: Engelborghs S – PersonEntity: Name: NameFull: Heilmann-Heimbach S – PersonEntity: Name: NameFull: Schmid M – PersonEntity: Name: NameFull: Tegos T – PersonEntity: Name: NameFull: Scarmeas N – PersonEntity: Name: NameFull: Dols-Icardo O – PersonEntity: Name: NameFull: Moreno F – PersonEntity: Name: NameFull: Pérez-Tur J – PersonEntity: Name: NameFull: Bullido MJ – PersonEntity: Name: NameFull: Sánchez-Valle R – PersonEntity: Name: NameFull: Álvarez V – PersonEntity: Name: NameFull: García-González P – PersonEntity: Name: NameFull: Mir P – PersonEntity: Name: NameFull: Real LM – PersonEntity: Name: NameFull: Piñol-Ripoll G – PersonEntity: Name: NameFull: García-Alberca JM – PersonEntity: Name: NameFull: Seelaar H – PersonEntity: Name: NameFull: Ramakers I – PersonEntity: Name: NameFull: Papma J – PersonEntity: Name: NameFull: Hulsman M – PersonEntity: Name: NameFull: Laske C – PersonEntity: Name: NameFull: Teipel S – PersonEntity: Name: NameFull: Priller J – PersonEntity: Name: NameFull: Perneczky R – PersonEntity: Name: NameFull: Buerger K – PersonEntity: Name: NameFull: Nöthen MM – PersonEntity: Name: NameFull: Lewczuk P – PersonEntity: Name: NameFull: Kornhuber J – PersonEntity: Name: NameFull: Hampel H – PersonEntity: Name: NameFull: Giegling I – PersonEntity: Name: NameFull: Goldhardt O – PersonEntity: Name: NameFull: Diehl-Schmid J – PersonEntity: Name: NameFull: Andrade V – PersonEntity: Name: NameFull: Heneka MM – PersonEntity: Name: NameFull: Frölich L – PersonEntity: Name: NameFull: Vogelgsang J – PersonEntity: Name: NameFull: Graff C – PersonEntity: Name: NameFull: Thonberg H – PersonEntity: Name: NameFull: Ullgren A – PersonEntity: Name: NameFull: Papenberg G – PersonEntity: Name: NameFull: Deleuze JF – PersonEntity: Name: NameFull: Dufouil C – PersonEntity: Name: NameFull: Wagner M – PersonEntity: Name: NameFull: Jessen F – PersonEntity: Name: NameFull: Holstege H – PersonEntity: Name: NameFull: van Duijn C – PersonEntity: Name: NameFull: Lebouvier T – PersonEntity: Name: NameFull: Hannon O – PersonEntity: Name: NameFull: Leinonen V – PersonEntity: Name: NameFull: Soininen H – PersonEntity: Name: NameFull: Herukka SK – PersonEntity: Name: NameFull: Giedraitis V – PersonEntity: Name: NameFull: Löwenmark M – PersonEntity: Name: NameFull: Kilander L – PersonEntity: Name: NameFull: Genius P – PersonEntity: Name: NameFull: Rodríguez B – PersonEntity: Name: NameFull: Luckett ES – PersonEntity: Name: NameFull: Navarro A – PersonEntity: Name: NameFull: Cano A – PersonEntity: Name: NameFull: Marquié M – PersonEntity: Name: NameFull: Blennow K – PersonEntity: Name: NameFull: Zetterberg H – PersonEntity: Name: NameFull: Lleo A – PersonEntity: Name: NameFull: Boada M – PersonEntity: Name: NameFull: Ruiz A – PersonEntity: Name: NameFull: Lee VM – PersonEntity: Name: NameFull: Van Deerlin VM – PersonEntity: Name: NameFull: Deming Y – PersonEntity: Name: NameFull: Johnson SC – PersonEntity: Name: NameFull: Engelman CD – PersonEntity: Name: NameFull: Pastor P – PersonEntity: Name: NameFull: Alvarez I – PersonEntity: Name: NameFull: Peskind ER – PersonEntity: Name: NameFull: Heslegrave AJ – PersonEntity: Name: NameFull: Saykin AJ – PersonEntity: Name: NameFull: Nho K – PersonEntity: Name: NameFull: Schindler SE – PersonEntity: Name: NameFull: Morris JC – PersonEntity: Name: NameFull: Holtzman DM – PersonEntity: Name: NameFull: McDade E – PersonEntity: Name: NameFull: Renton AE – PersonEntity: Name: NameFull: Goate A – PersonEntity: Name: NameFull: Ibanez L – PersonEntity: Name: NameFull: Riemenschneider M – PersonEntity: Name: NameFull: Albert MS – PersonEntity: Name: NameFull: Laws SM – PersonEntity: Name: NameFull: Porter T – PersonEntity: Name: NameFull: O'Brien EK – PersonEntity: Name: NameFull: Shaw LM – PersonEntity: Name: NameFull: Tijms BM – PersonEntity: Name: NameFull: Ingelsson M – PersonEntity: Name: NameFull: Visser PJ – PersonEntity: Name: NameFull: Hiltunen M – PersonEntity: Name: NameFull: Sleegers K – PersonEntity: Name: NameFull: Ritchie CW – PersonEntity: Name: NameFull: Sims R – PersonEntity: Name: NameFull: Belloy M – PersonEntity: Name: NameFull: Lambert JC – PersonEntity: Name: NameFull: Vilor-Tejedor N – PersonEntity: Name: NameFull: Fernández MV – PersonEntity: Name: NameFull: Li QS – PersonEntity: Name: NameFull: Nagle MW – PersonEntity: Name: NameFull: Marioni RE – PersonEntity: Name: NameFull: Ramirez A – PersonEntity: Name: NameFull: Bertram L – PersonEntity: Name: NameFull: van der Lee SJ – PersonEntity: Name: NameFull: Cruchaga C IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 04 Text: 2026 Apr 21 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2041-1723 Titles: – TitleFull: Nature communications Type: main |
| ResultId | 1 |
