EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform.
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| Title: | EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform. |
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| Authors: | Waltman P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Chandra P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Eng KW; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Field Applications Department, Illumina, Ann Arbor, MI, USA., Wilkes DC; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Park H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Pabon C; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Delpe P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Bhinder B; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Manohar J; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Kane T; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Fernandez E; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Gorski K; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Greco N; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Simi M; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Tang JM; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Zisimopoulos P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., King A; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Al Assaad M; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Ten Eyck T; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Roberts D; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Monge J; WCM Myeloma Center, Weill Cornell Medicine, New York, NY, USA., Demichelis F; Department of Cellular, Computational, and Integrative Biology, Interdepartmental Center of Medical Sciences (CISMed), University of Trento, Trento, Italy., Tam W; Department of Anatomic Pathology, Hematopathology, Molecular Genetic Pathology, Northwell Health, New York, NY, USA., Ouseph MM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Sigaras A; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Beltran H; Department of Medicine, Dana-Farber Cancer Institute, Boston, MA, USA., Rennert H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Lindeman N; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Song W; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Solomon J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Mosquera JM; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Kim R; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Catalano J; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Hassane DC; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Sigouros M; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Elemento O; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Alonso A; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sboner A; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 21; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42014463 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Waltman+P%22">Waltman P</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chandra+P%22">Chandra P</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Eng+KW%22">Eng KW</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Field Applications Department, Illumina, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Wilkes+DC%22">Wilkes DC</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Park+H%22">Park H</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pabon+C%22">Pabon C</searchLink>; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA.<br /><searchLink fieldCode="AU" term="%22Delpe+P%22">Delpe P</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bhinder+B%22">Bhinder B</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Manohar+J%22">Manohar J</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kane+T%22">Kane T</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez+E%22">Fernandez E</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gorski+K%22">Gorski K</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Greco+N%22">Greco N</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Simi+M%22">Simi M</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tang+JM%22">Tang JM</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zisimopoulos+P%22">Zisimopoulos P</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22King+A%22">King A</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Al+Assaad+M%22">Al Assaad M</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ten+Eyck+T%22">Ten Eyck T</searchLink>; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+D%22">Roberts D</searchLink>; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA.<br /><searchLink fieldCode="AU" term="%22Monge+J%22">Monge J</searchLink>; WCM Myeloma Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Demichelis+F%22">Demichelis F</searchLink>; Department of Cellular, Computational, and Integrative Biology, Interdepartmental Center of Medical Sciences (CISMed), University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Tam+W%22">Tam W</searchLink>; Department of Anatomic Pathology, Hematopathology, Molecular Genetic Pathology, Northwell Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ouseph+MM%22">Ouseph MM</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sigaras+A%22">Sigaras A</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Beltran+H%22">Beltran H</searchLink>; Department of Medicine, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rennert+H%22">Rennert H</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lindeman+N%22">Lindeman N</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Song+W%22">Song W</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Solomon+J%22">Solomon J</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mosquera+JM%22">Mosquera JM</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kim+R%22">Kim R</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Catalano+J%22">Catalano J</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hassane+DC%22">Hassane DC</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sigouros+M%22">Sigouros M</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Elemento+O%22">Elemento O</searchLink>; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Alonso+A%22">Alonso A</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sboner+A%22">Sboner A</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Apr 21; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Apr 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41698-026-01390-5 Languages: – Code: eng Text: English Titles: – TitleFull: EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Waltman P – PersonEntity: Name: NameFull: Chandra P – PersonEntity: Name: NameFull: Eng KW – PersonEntity: Name: NameFull: Wilkes DC – PersonEntity: Name: NameFull: Park H – PersonEntity: Name: NameFull: Pabon C – PersonEntity: Name: NameFull: Delpe P – PersonEntity: Name: NameFull: Bhinder B – PersonEntity: Name: NameFull: Manohar J – PersonEntity: Name: NameFull: Kane T – PersonEntity: Name: NameFull: Fernandez E – PersonEntity: Name: NameFull: Gorski K – PersonEntity: Name: NameFull: Greco N – PersonEntity: Name: NameFull: Simi M – PersonEntity: Name: NameFull: Tang JM – PersonEntity: Name: NameFull: Zisimopoulos P – PersonEntity: Name: NameFull: King A – PersonEntity: Name: NameFull: Al Assaad M – PersonEntity: Name: NameFull: Ten Eyck T – PersonEntity: Name: NameFull: Roberts D – PersonEntity: Name: NameFull: Monge J – PersonEntity: Name: NameFull: Demichelis F – PersonEntity: Name: NameFull: Tam W – PersonEntity: Name: NameFull: Ouseph MM – PersonEntity: Name: NameFull: Sigaras A – PersonEntity: Name: NameFull: Beltran H – PersonEntity: Name: NameFull: Rennert H – PersonEntity: Name: NameFull: Lindeman N – PersonEntity: Name: NameFull: Song W – PersonEntity: Name: NameFull: Solomon J – PersonEntity: Name: NameFull: Mosquera JM – PersonEntity: Name: NameFull: Kim R – PersonEntity: Name: NameFull: Catalano J – PersonEntity: Name: NameFull: Hassane DC – PersonEntity: Name: NameFull: Sigouros M – PersonEntity: Name: NameFull: Elemento O – PersonEntity: Name: NameFull: Alonso A – PersonEntity: Name: NameFull: Sboner A IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 04 Text: 2026 Apr 21 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2397-768X Numbering: – Type: volume Value: 10 – Type: issue Value: 1 Titles: – TitleFull: NPJ precision oncology Type: main |
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