EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform.

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Title: EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform.
Authors: Waltman P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Chandra P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Eng KW; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Field Applications Department, Illumina, Ann Arbor, MI, USA., Wilkes DC; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Park H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Pabon C; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Delpe P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Bhinder B; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Manohar J; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Kane T; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Fernandez E; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Gorski K; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Greco N; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Simi M; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Tang JM; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Zisimopoulos P; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., King A; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Al Assaad M; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Ten Eyck T; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Roberts D; Diagnostics and Genomics Group, Agilent Technologies, Santa Clara, CA, USA., Monge J; WCM Myeloma Center, Weill Cornell Medicine, New York, NY, USA., Demichelis F; Department of Cellular, Computational, and Integrative Biology, Interdepartmental Center of Medical Sciences (CISMed), University of Trento, Trento, Italy., Tam W; Department of Anatomic Pathology, Hematopathology, Molecular Genetic Pathology, Northwell Health, New York, NY, USA., Ouseph MM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Sigaras A; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Beltran H; Department of Medicine, Dana-Farber Cancer Institute, Boston, MA, USA., Rennert H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Lindeman N; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Song W; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Solomon J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Mosquera JM; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Kim R; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Catalano J; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Hassane DC; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Sigouros M; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Elemento O; Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Alonso A; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sboner A; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 21; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
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  Data: EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform.
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Department of System and Computational Biology, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Alonso+A%22">Alonso A</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sboner+A%22">Sboner A</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. ans2077@med.cornell.edu.
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