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TTLL12 counteracts BPOZ-2 to stabilize eEF1A1 and promote hepatocarcinogenesis.

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Title: TTLL12 counteracts BPOZ-2 to stabilize eEF1A1 and promote hepatocarcinogenesis.
Authors: Leng K; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China., Yang Z; Department of Colorectal Surgery, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China., Liming Y; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China., Meng N; Department of Colorectal Oncological Surgery, Cancer Center, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Xu Y; Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. xuyihrb@pathology.hku.hk.; Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, China. xuyihrb@pathology.hku.hk.; State Key Laboratory of Oncology in South China, Cancer Center of Sun Yat-Sen University, Guangzhou, China. xuyihrb@pathology.hku.hk.; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China. xuyihrb@pathology.hku.hk.; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. xuyihrb@pathology.hku.hk., Liao G; Department of Hepatobiliary Surgery, Foshan Hospital Affiliated to Southern Medical University, Foshan, China. liaoguanqun@gmail.com., Han M; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, China. hanmei@qdu.edu.cn., Shi G; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China. sgjzp@hotmail.com.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China. sgjzp@hotmail.com.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 21. Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TTLL12 counteracts BPOZ-2 to stabilize eEF1A1 and promote hepatocarcinogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Leng+K%22">Leng K</searchLink>; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Department of Colorectal Surgery, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Liming+Y%22">Liming Y</searchLink>; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Meng+N%22">Meng N</searchLink>; Department of Colorectal Oncological Surgery, Cancer Center, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. xuyihrb@pathology.hku.hk.; Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, China. xuyihrb@pathology.hku.hk.; State Key Laboratory of Oncology in South China, Cancer Center of Sun Yat-Sen University, Guangzhou, China. xuyihrb@pathology.hku.hk.; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China. xuyihrb@pathology.hku.hk.; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. xuyihrb@pathology.hku.hk.<br /><searchLink fieldCode="AU" term="%22Liao+G%22">Liao G</searchLink>; Department of Hepatobiliary Surgery, Foshan Hospital Affiliated to Southern Medical University, Foshan, China. liaoguanqun@gmail.com.<br /><searchLink fieldCode="AU" term="%22Han+M%22">Han M</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, China. hanmei@qdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Shi+G%22">Shi G</searchLink>; Department of Hepatopancreatobiliary Surgery, Qingdao Municipal Hospital, Qingdao University, Qingdao, PR China. sgjzp@hotmail.com.; Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China. sgjzp@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 21. <i>Date of Electronic Publication: </i>2026 Apr 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08694-1
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      – TitleFull: TTLL12 counteracts BPOZ-2 to stabilize eEF1A1 and promote hepatocarcinogenesis.
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              Text: 2026 Apr 21
              Type: published
              Y: 2026
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