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Machine learning model based on plasma proteomics for the identification of Parkinson's disease.

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Title: Machine learning model based on plasma proteomics for the identification of Parkinson's disease.
Authors: Adewale B; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Chia R; Neuromuscular Diseases Research Section, National Institute on Aging, Bethesda, MD 20892, USA., Moaddel R; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD 21224, USA., Landeck N; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Rasheed M; Neuromuscular Diseases Research Section, National Institute on Aging, Bethesda, MD 20892, USA., Alba C; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD 20814, USA.; The American Genome Center, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD 20814, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD 20817, USA., Reho P; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA., Vasta R; Neuromuscular Diseases Research Section, National Institute on Aging, Bethesda, MD 20892, USA.; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy., Calvo A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy.; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, 10126 Torino, Italy., Moglia C; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy.; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, 10126 Torino, Italy., Canosa A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy.; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, 10126 Torino, Italy.; Institute of Cognitive Sciences and Technologies, C.N.R., 00196 Roma, Italy., Manera U; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy.; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, 10126 Torino, Italy., Snyder A; Neurodegenerative Disorders Clinic, Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Lee YJ; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.; Division of Neurology, Department of Medicine, Taipei City Hospital, Renai Branch, Taipei City 106243, Taiwan., Grassano M; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Gao C; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Zhu M; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD 21224, USA., Brunetti M; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy., Casale F; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy., Arvind K; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Dawson TM; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Neuroregeneration and Stem Cell Programs, Institute of Cell Engineering, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA.; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA., Rosenthal LS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Hall AJ; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pantelyat AY; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Ding J; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Gibbs JR; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD 21224, USA., Candia J; Longitudinal Studies Section, National Institute on Aging, Baltimore, MD 21224, USA., Tanaka T; Longitudinal Studies Section, National Institute on Aging, Baltimore, MD 21224, USA., Ferrucci L; Longitudinal Studies Section, National Institute on Aging, Baltimore, MD 21224, USA., Chiò A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, 10126 Torino, Italy.; Institute of Cognitive Sciences and Technologies, C.N.R., Via S. Martino della Battaglia, 00185 Roma, Italy.; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Corso Bramante, 10126 Torino, Italy., Narendra DP; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Kwan JY; Neurodegenerative Disorders Clinic, Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Ehrlich DJ; Parkinson's Disease Clinic, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Dalgard CL; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD 20814, USA.; The American Genome Center, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD 20814, USA., Traynor BJ; Neuromuscular Diseases Research Section, National Institute on Aging, Bethesda, MD 20892, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; RNA Therapeutics Laboratory, Therapeutics Development Branch, National Center for Advancing Translational Sciences, Rockville, MD 20850, USA., Scholz SW; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Corporate Authors: American Genome Center
Source: Brain : a journal of neurology [Brain] 2026 Apr 22. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Machine learning model based on plasma proteomics for the identification of Parkinson's disease.
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