Early Inflammatory Biomarkers Associated With Functional Outcomes in Acute Cerebral Venous Thrombosis: CLOT-VENUS Substudy.

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Title: Early Inflammatory Biomarkers Associated With Functional Outcomes in Acute Cerebral Venous Thrombosis: CLOT-VENUS Substudy.
Authors: Cruz-Criollo L; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Galecio-Castillo M; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Rodriguez-Calienes A; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).; Facultad de Medicina Humana, Universidad Cientifica del Sur, Lima, Peru (A.R.-C.)., Kalakoti P; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Cano-Nigenda V; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.).; Doctoral Program in Medical Sciences, Faculty of Medicine, Universidad Nacional Autónoma de Mexico (UNAM), Mexico City (V.C.-N.)., Brito A; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Barboza MA; Department of Neurosciences, Hospital Dr. Rafael A. Calderon Guardia, San Jose, Costa Rica (M.A.B.)., Gao J; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Mercado A; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.)., Pereda-Castillo A; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.)., Lefkowitz J; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Cespedes J; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Abdelhakim N; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Zheng-Lin B; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR (B.Z.-L.)., Shaban A; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.)., Smith BJ; Department of Biostatisti cs, University of Iowa, Iowa City (B.J.S.), University of Iowa Health Care, Iowa City., Mohr NM; Department of Emergency Medicine (N.M.M.), University of Iowa Health Care, Iowa City.; Department of Epidemiology, University of Iowa, Iowa City (N.M.M.).; Division of Critical Care, Department of Anesthesia, Department of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City (N.M.M.)., Arauz A; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.)., Ortega-Gutierrez S; Department of Neurology, Neurosurgery and Radiology (S.O.-G.), University of Iowa Health Care, Iowa City.
Source: Stroke [Stroke] 2026 Jun; Vol. 57 (6), pp. 1632-1642. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cruz-Criollo+L%22">Cruz-Criollo L</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Galecio-Castillo+M%22">Galecio-Castillo M</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Rodriguez-Calienes+A%22">Rodriguez-Calienes A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).; Facultad de Medicina Humana, Universidad Cientifica del Sur, Lima, Peru (A.R.-C.).<br /><searchLink fieldCode="AU" term="%22Kalakoti+P%22">Kalakoti P</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Cano-Nigenda+V%22">Cano-Nigenda V</searchLink>; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.).; Doctoral Program in Medical Sciences, Faculty of Medicine, Universidad Nacional Autónoma de Mexico (UNAM), Mexico City (V.C.-N.).<br /><searchLink fieldCode="AU" term="%22Brito+A%22">Brito A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Barboza+MA%22">Barboza MA</searchLink>; Department of Neurosciences, Hospital Dr. Rafael A. Calderon Guardia, San Jose, Costa Rica (M.A.B.).<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Mercado+A%22">Mercado A</searchLink>; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.).<br /><searchLink fieldCode="AU" term="%22Pereda-Castillo+A%22">Pereda-Castillo A</searchLink>; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.).<br /><searchLink fieldCode="AU" term="%22Lefkowitz+J%22">Lefkowitz J</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Cespedes+J%22">Cespedes J</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Abdelhakim+N%22">Abdelhakim N</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Zheng-Lin+B%22">Zheng-Lin B</searchLink>; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR (B.Z.-L.).<br /><searchLink fieldCode="AU" term="%22Shaban+A%22">Shaban A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City (L.C.-C., M.G.-C., A.R.-C., P.K., A.B., J.G., J.L., J.C., N.A., A.S.).<br /><searchLink fieldCode="AU" term="%22Smith+BJ%22">Smith BJ</searchLink>; Department of Biostatisti cs, University of Iowa, Iowa City (B.J.S.), University of Iowa Health Care, Iowa City.<br /><searchLink fieldCode="AU" term="%22Mohr+NM%22">Mohr NM</searchLink>; Department of Emergency Medicine (N.M.M.), University of Iowa Health Care, Iowa City.; Department of Epidemiology, University of Iowa, Iowa City (N.M.M.).; Division of Critical Care, Department of Anesthesia, Department of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City (N.M.M.).<br /><searchLink fieldCode="AU" term="%22Arauz+A%22">Arauz A</searchLink>; Stroke Clinic, Department of Neurology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City (V.C.-N., A.M., A.P.-C, A.A.).<br /><searchLink fieldCode="AU" term="%22Ortega-Gutierrez+S%22">Ortega-Gutierrez S</searchLink>; Department of Neurology, Neurosurgery and Radiology (S.O.-G.), University of Iowa Health Care, Iowa City.
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