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Modification of early behavioural, physiological and neuropathological endpoints by syntaxin-6 knockout in a humanised P301S transgenic model of tauopathy.

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Title: Modification of early behavioural, physiological and neuropathological endpoints by syntaxin-6 knockout in a humanised P301S transgenic model of tauopathy.
Authors: Hill E; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Linehan J; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Farmer M; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Jakubcova T; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Hamdan S; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Tomlinson A; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Purro S; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Argentina F; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Jones E; School of Biochemistry, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK., Kaye N; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Fitzhugh C; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., de Silva R; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Brandner S; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Collinge J; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Cunningham TJ; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK., Mead S; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK. s.mead@prion.ucl.ac.uk.
Source: Acta neuropathologica [Acta Neuropathol] 2026 Apr 22; Vol. 151 (1). Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Modification of early behavioural, physiological and neuropathological endpoints by syntaxin-6 knockout in a humanised P301S transgenic model of tauopathy.
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  Data: <searchLink fieldCode="AU" term="%22Hill+E%22">Hill E</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Linehan+J%22">Linehan J</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Farmer+M%22">Farmer M</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Jakubcova+T%22">Jakubcova T</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Hamdan+S%22">Hamdan S</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Tomlinson+A%22">Tomlinson A</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Purro+S%22">Purro S</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Argentina+F%22">Argentina F</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Jones+E%22">Jones E</searchLink>; School of Biochemistry, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Kaye+N%22">Kaye N</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Fitzhugh+C%22">Fitzhugh C</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22de+Silva+R%22">de Silva R</searchLink>; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Brandner+S%22">Brandner S</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Collinge+J%22">Collinge J</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Cunningham+TJ%22">Cunningham TJ</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK.<br /><searchLink fieldCode="AU" term="%22Mead+S%22">Mead S</searchLink>; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Courtauld Building, 33 Cleveland Street, London, W1W 7FF, UK. s.mead@prion.ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2026 Apr 22; Vol. 151 (1). <i>Date of Electronic Publication: </i>2026 Apr 22.
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