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A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma.

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Title: A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma.
Authors: Friske JD; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee., Cuisin F; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Magistère Européen de Génétique, Universite Paris Cite, Paris, France., Guernalec P; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Magistère Européen de Génétique, Universite Paris Cite, Paris, France., Malone HA; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Nance S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Bennett D; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Burden SJ; Cytogenetics Core Facility, St. Jude Children's Research Hospital, Memphis, Tennessee., Chang TC; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee., Shi H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee., Williams JS; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Valentine V; Cytogenetics Core Facility, St. Jude Children's Research Hospital, Memphis, Tennessee., Passaia BDS; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Ju B; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Adetunji MO; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Geeleher P; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Abraham BJ; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Wu G; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee., Li C; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee., Roussel MF; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.
Source: Cancer research [Cancer Res] 2026 Jul 02; Vol. 86 (13), pp. 3160-3178.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Friske+JD%22">Friske JD</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Cuisin+F%22">Cuisin F</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Magistère Européen de Génétique, Universite Paris Cite, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guernalec+P%22">Guernalec P</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Magistère Européen de Génétique, Universite Paris Cite, Paris, France.<br /><searchLink fieldCode="AU" term="%22Malone+HA%22">Malone HA</searchLink>; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Nance+S%22">Nance S</searchLink>; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Bennett+D%22">Bennett D</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Burden+SJ%22">Burden SJ</searchLink>; Cytogenetics Core Facility, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Chang+TC%22">Chang TC</searchLink>; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Williams+JS%22">Williams JS</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Valentine+V%22">Valentine V</searchLink>; Cytogenetics Core Facility, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Passaia+BDS%22">Passaia BDS</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Ju+B%22">Ju B</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Adetunji+MO%22">Adetunji MO</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Geeleher+P%22">Geeleher P</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Abraham+BJ%22">Abraham BJ</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Wu+G%22">Wu G</searchLink>; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Roussel+MF%22">Roussel MF</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, Memphis, Tennessee.
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  Data: <searchLink fieldCode="JN" term="%222984705R%22">Cancer research</searchLink> [Cancer Res] 2026 Jul 02; Vol. 86 (13), pp. 3160-3178.
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