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Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma: A Randomized Clinical Trial.

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Title: Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma: A Randomized Clinical Trial.
Authors: Xu PP; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics; National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Song YQ; Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China., Shen JZ; Fujian Medical University Union Hospital, Fuzhou, China., Cai QQ; Sun Yat-sen University Cancer Center, Guangzhou, China., Zhou H; Hunan Cancer Hospital, Changsha, China., Zhang LL; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Xiang Y; Chongqing University Cancer Hospital, Chongqing, China., Sun XH; The Second Hospital of Dalian Medical University, Dalian, China., Yang W; Shengjing Hospital of China Medical University, Liaoning, China., Yao ZH; Henan Cancer Hospital, Zhengzhou, China., Jing HM; Peking University Third Hospital, Beijing, China., Wen SJ; Xinjiang Medical University Affiliated Tumor Hospital, Wulumuqi, China., Jin J; The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Xue HW; The Affiliated Hospital of Qingdao University, Qingdao, China., Cen H; Guangxi Medical University Affiliated Cancer Hospital, Nanning, China., Ding KY; The First Affiliated Hospital of USTC, Hefei, China., Jin ZM; The First Affiliated Hospital of Soochow University, Suzhou, China., Liu LH; The Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China., Xing XJ; Liaoning Cancer Hospital & Institute, Shenyang, China., Li LF; Tianjin Medical University Cancer Institute and Hospital, Tianjin, China., Hou M; Qilu Hospital of Shandong University, Jinan, China., Liu L; The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Zhang MZ; The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Li WY; Guangdong Provincial People's Hospital, Guangdong, China., Bai O; The First Hospital of Jilin University, Changchun, China., Feng R; Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhu ZM; Henan Provincial People's Hospital, Zhengzhou, China., Wu HJ; Hubei Cancer Center, Wuhan, China., Su LP; Shanxi Cancer Hospital, Taiyuan, China., Gao L; The Second Affiliated Hospital of Army Medical University, Chongqing, China., Li F; The First Affiliated Hospital of Nanchang University, Nanchang, China., Huang WR; The First Medical Center of Chinese PLA General Hospital, Beijing, China., Liu P; Zhongshan Hospital Fudan University, Shanghai, China., Yan XJ; First Hospital of China Medical University, Shenyang, China., Zhao Y; The First People's Hospital of Foshan, Foshan, China., Su H; The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China., Zhao XL; Xiangya Hospital, Central South University, Changsha, China., Fu R; Tianjin Medical University General Hospital, Tianjin, China., Liu H; Affiliated Hospital of Nantong University, Nantong, China., Shi WY; Affiliated Hospital of Nantong University, Nantong, China., Li HZ; Chipscreen Biosciences Ltd, Shenzhen, China., Chen B; Chipscreen Biosciences Ltd, Shenzhen, China., Ning ZQ; Chipscreen Biosciences Ltd, Shenzhen, China., Zhu J; Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China., Zhao WL; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics; National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Source: JAMA [JAMA] 2026 May 19; Vol. 335 (19), pp. 1684-1693.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Comparative Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Xu+PP%22">Xu PP</searchLink>; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics; National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Song+YQ%22">Song YQ</searchLink>; Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Shen+JZ%22">Shen JZ</searchLink>; Fujian Medical University Union Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Cai+QQ%22">Cai QQ</searchLink>; Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Hunan Cancer Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Zhang+LL%22">Zhang LL</searchLink>; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xiang+Y%22">Xiang Y</searchLink>; Chongqing University Cancer Hospital, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Sun+XH%22">Sun XH</searchLink>; The Second Hospital of Dalian Medical University, Dalian, China.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Shengjing Hospital of China Medical University, Liaoning, China.<br /><searchLink fieldCode="AU" term="%22Yao+ZH%22">Yao ZH</searchLink>; Henan Cancer Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Jing+HM%22">Jing HM</searchLink>; Peking University Third Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wen+SJ%22">Wen SJ</searchLink>; Xinjiang Medical University Affiliated Tumor Hospital, Wulumuqi, China.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xue+HW%22">Xue HW</searchLink>; The Affiliated Hospital of Qingdao University, Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Cen+H%22">Cen H</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2026 May 19; Vol. 335 (19), pp. 1684-1693.
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