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Peripheral blood transcriptional profiling predicts tumor subtype and neoadjuvant chemoimmunotherapy outcomes in human breast cancer.

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Title: Peripheral blood transcriptional profiling predicts tumor subtype and neoadjuvant chemoimmunotherapy outcomes in human breast cancer.
Authors: Sun X; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA., Ocampo AA; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA., Hanna A; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Taylor BC; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA., Marshall JL; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA., Steele JA; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA., Axelrod ML; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Wescott EC; Departments of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Opalenik SR; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., DeMichele A; University of Pennsylvania, Philadelphia, PA 19104, USA., Esserman LJ; University of California San Francisco, San Francisco, CA 94115, USA., Liu MC; Natera Inc., San Carlos, CA 94070, USA., Nanda R; University of Chicago, Chicago, IL 60637, USA., Wolf DM; University of California San Francisco, San Francisco, CA 94115, USA., Brown Swigart L; University of California San Francisco, San Francisco, CA 94115, USA., Hirst GL; University of California San Francisco, San Francisco, CA 94115, USA., van 't Veer LJ; University of California San Francisco, San Francisco, CA 94115, USA., Xu Y; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Balko JM; Departments of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Apr 22; Vol. 18 (846), pp. eaec2358. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Peripheral blood transcriptional profiling predicts tumor subtype and neoadjuvant chemoimmunotherapy outcomes in human breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Ocampo+AA%22">Ocampo AA</searchLink>; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Hanna+A%22">Hanna A</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+BC%22">Taylor BC</searchLink>; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Marshall+JL%22">Marshall JL</searchLink>; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Steele+JA%22">Steele JA</searchLink>; Cancer Biology Program Vanderbilt University, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Axelrod+ML%22">Axelrod ML</searchLink>; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Wescott+EC%22">Wescott EC</searchLink>; Departments of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Opalenik+SR%22">Opalenik SR</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22DeMichele+A%22">DeMichele A</searchLink>; University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Esserman+LJ%22">Esserman LJ</searchLink>; University of California San Francisco, San Francisco, CA 94115, USA.<br /><searchLink fieldCode="AU" term="%22Liu+MC%22">Liu MC</searchLink>; Natera Inc., San Carlos, CA 94070, USA.<br /><searchLink fieldCode="AU" term="%22Nanda+R%22">Nanda R</searchLink>; University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Wolf+DM%22">Wolf DM</searchLink>; University of California San Francisco, San Francisco, CA 94115, USA.<br /><searchLink fieldCode="AU" term="%22Brown+Swigart+L%22">Brown Swigart L</searchLink>; University of California San Francisco, San Francisco, CA 94115, USA.<br /><searchLink fieldCode="AU" term="%22Hirst+GL%22">Hirst GL</searchLink>; University of California San Francisco, San Francisco, CA 94115, USA.<br /><searchLink fieldCode="AU" term="%22van+'t+Veer+LJ%22">van 't Veer LJ</searchLink>; University of California San Francisco, San Francisco, CA 94115, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Balko+JM%22">Balko JM</searchLink>; Departments of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Apr 22; Vol. 18 (846), pp. eaec2358. <i>Date of Electronic Publication: </i>2026 Apr 22.
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