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Three Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage.

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Title: Three Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage.
Authors: Anderson CS; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai.; George Institute for Global Health, University of New South Wales, Sydney.; Neurology Department, Royal Prince Alfred Hospital, Sydney., Chow CK; Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Westmead Hospital, Westmead, NSW, Australia., de Silva HA; Clinical Trials Unit, Department of Pharmacology, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka., Senanayake B; Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka., Wahab K; Department of Medicine, University of Ilorin, Ilorin, Nigeria., Al-Shahi Salman R; Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh., Klijn CJM; Department of Neurology, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center, Nijmegen, the Netherlands., Martins SO; Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.; Neurology Service Hospital Moinhos de Vento, Porto Alegre, Brazil., Espinosa N; George Institute for Global Health, University of New South Wales, Sydney., Kuhles L; George Institute for Global Health, University of New South Wales, Sydney., Billot L; George Institute for Global Health, University of New South Wales, Sydney.; School of Public Health, University of Bordeaux, Bordeaux, France., Arima H; Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Carcel C; George Institute for Global Health, University of New South Wales, Sydney., Wang X; George Institute for Global Health, University of New South Wales, Sydney., Li Q; George Institute for Global Health, University of New South Wales, Sydney., Shan S; George Institute for Global Health, University of New South Wales, Sydney., Shanthakumar M; George Institute for Global Health, University of New South Wales, Sydney., Nguyen HT; Stroke Unit, 115 Hospital, Ho Chi Minh City, Vietnam., Palliyaguruge D; Neurology Department, Teaching Hospital Kurunegala, Kurunegala, Sri Lanka., Peiris J; Neurology Department, National Hospital, Kandy, Sri Lanka., Ranawaka UK; Department of Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka., Bandusena S; Neurology Department, Kalubowila (Colombo South) Teaching Hospital, Dehiwala, Sri Lanka., Rajendiran T; Neurology Department, Kalubowila (Colombo South) Teaching Hospital, Dehiwala, Sri Lanka., Wijegunasinghe D; Department of Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka., Gunasekera H; Neurology Department, Sri Jayewardenepura General Hospital, Nugegoda, Sri Lanka., Wijeweera I; Neurology Department, National Hospital, Kandy, Sri Lanka., Dissanayake A; Neurology Department, Karapitiya Teaching Hospital, Galle, Sri Lanka., Keshavaraj A; Neurology Department, Jaffna Teaching Hospital, Jaffna, Sri Lanka., Obiako RO; Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria., Akinyemi R; Neuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria., Nasi L; Neurology Department, Hospital Moinhos de Vento, Porto Alegre, Brazil., Bazan R; Department of Neuroscience and Mental Health, Botucatu School of Medicine, Universidade Estadual Paulista, Botucatu, Brazil., Moro CHC; Neurology Department, Clinica Neurológica e Neurocirurgica de Joinville, Joinville, Brazil., Battaglini M; Neurology Department, Hospital de Base São José do Rio Preto, São José do Rio Preto, Brazil., Zétola V; Federal University of Parana, Curitiba, Brazil., Law WC; Neurology Department, Sarawak General Hospital, Jalan Hospital, Kuching, Malaysia., Chia YK; Neurology Department, Queen Elizabeth Hospital, Kota Kinabalu, Malaysia., Cordato D; Neurology Department, Liverpool Hospital, Liverpool, NSW, Australia.; Faculty of Medicine, University of New South Wales, Sydney., Grimley R; Department of Neurology, Sunshine Coast University Hospital, Sunshine Coast, QLD, Australia.; School of Medicine and Dentistry, Griffith University, Birtinya, QLD, Australia., Dahanayaka A; RemediumOne Contract Research Organization, Colombo, Sri Lanka., Liyanagamage S; RemediumOne Contract Research Organization, Colombo, Sri Lanka., Fernando N; Peradeniya Teaching Hospital, Kandy, Sri Lanka., Rasheed NA; Neurology Department, Gampaha District General Hospital, Gampaha, Sri Lanka., Kakabadze N; Urgent Neurological Clinic 'Neurology,' Tbilisi State Medical University, Tbilisi, Georgia., Beridze M; First University Clinic, Tbilisi State Medical University, Tbilisi, Georgia., Aravinthan M; Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka., Sahathevan V; Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka., Wijesundara D; Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka., Ruwanpathirana P; Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka., Wan Zaidi WA; Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Kherkheulidze T; Urgent Neurological Clinic 'Neurology,' Tbilisi State Medical University, Tbilisi, Georgia., Fischer U; Department of Neurology, University Hospital Bern and University of Bern, Bern, Switzerland., de Souza AC; Neurology Service Hospital Moinhos de Vento, Porto Alegre, Brazil., Lee TH; Stroke Center and Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Chen C; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Pontes-Neto O; Department of Neurosciences and Behavioral Sciences, Ribeirao Preto School of Medicine, University of São Paulo, Ribeirao Preto, Brazil., Robinson T; College of Life Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health and Care Research Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Wang J; Center for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai., Naismith SL; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Charles Perkins Centre, University of Sydney, Sydney., Barnett M; Neurology Department, Royal Prince Alfred Hospital, Sydney.; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia., Delfino C; George Institute for Global Health, University of New South Wales, Sydney.; Centro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile., You S; Department of Neurology and Clinical Research Center of Neurologic Disease, Second Affiliated Hospital of Soochow University, Suzhou, China., Liu F; Department of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai., Delcourt C; George Institute for Global Health, University of New South Wales, Sydney.; Department of Clinical Medicine, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney., Moullaali TJ; Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh., Wilkinson T; Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh., Watson N; Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh., Santo K; Academic Research Organization, Hospital Israelita Albert Einstein, São Paulo., Han Q; George Institute for Global Health, University of New South Wales, Sydney., Souza MA; Neurology Department, Hospital Moinhos de Vento, Porto Alegre, Brazil., Jolink WMT; Department of Neurology, Isala Hospital, Zwolle, the Netherlands., Cristofari AB; Universidade de Lisboa, Lisbon, Portugal., Zhou Z; George Institute for Global Health, University of New South Wales, Sydney., Schreuder FH; Department of Neurology, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center, Nijmegen, the Netherlands., Lindley RI; George Institute for Global Health, University of New South Wales, Sydney.; Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Westmead Hospital, Westmead, NSW, Australia., Armenis M; George Institute for Global Health, University of New South Wales, Sydney., Woodward M; George Institute for Global Health, University of New South Wales, Sydney.; George Institute for Global Health, School of Public Health, Imperial College London, London., Freed R; George Institute for Global Health, University of New South Wales, Sydney., Song L; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai.; George Institute for Global Health, University of New South Wales, Sydney., Chalmers J; George Institute for Global Health, University of New South Wales, Sydney., Rodgers A; George Institute for Global Health, University of New South Wales, Sydney.; George Institute for Global Health, School of Public Health, Imperial College London, London.
Corporate Authors: Trident Research Group
Source: The New England journal of medicine [N Engl J Med] 2026 Apr 23; Vol. 394 (16), pp. 1571-1582.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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            – D: 23
              M: 04
              Text: 2026 Apr 23
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1533-4406
          Numbering:
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              Value: 394
            – Type: issue
              Value: 16
          Titles:
            – TitleFull: The New England journal of medicine
              Type: main
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