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Osteoarthritic synovial fibroblasts drive inflammatory responses and impair chondrocyte function in response to a fibronectin matrikine.

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Title: Osteoarthritic synovial fibroblasts drive inflammatory responses and impair chondrocyte function in response to a fibronectin matrikine.
Authors: Fernandez Davila JG; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: jfernan@email.unc.edu., Alberto RA; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: ra3108@cumc.columbia.edu., Byun S; Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC, USA. Electronic address: sbyun@unc.edu., D'Costa S; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: susan_dcosta@med.unc.edu., Shine J; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: yalins@med.unc.edu., Alvarez C; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: alvarec@emaill.edu., Yanke AB; Department of Orthopedics, Rush University Medical Center, Chicago, IL, USA. Electronic address: adam.yanke@rushortho.com., Olcott CW; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Department of Orthopedics, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: chistopher_olcott@med.unc.edu., Diekman BO; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Lampe Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, NC, USA. Electronic address: bdiekman@email.unc.edu., Phanstiel DH; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC, USA; Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: douglas_phanstiel@med.unc.edu., Loeser RF; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Division of Rheumatology, Allergy and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: richard_loeser@med.unc.edu.
Source: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2026 Aug; Vol. 34 (8), pp. 1195-1208. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders For The Osteoarthritis Research Society Country of Publication: England NLM ID: 9305697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9653 (Electronic) Linking ISSN: 10634584 NLM ISO Abbreviation: Osteoarthritis Cartilage Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Fernandez+Davila+JG%22">Fernandez Davila JG</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: jfernan@email.unc.edu.<br /><searchLink fieldCode="AU" term="%22Alberto+RA%22">Alberto RA</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: ra3108@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Byun+S%22">Byun S</searchLink>; Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC, USA. Electronic address: sbyun@unc.edu.<br /><searchLink fieldCode="AU" term="%22D'Costa+S%22">D'Costa S</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: susan_dcosta@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Shine+J%22">Shine J</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: yalins@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Alvarez+C%22">Alvarez C</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: alvarec@emaill.edu.<br /><searchLink fieldCode="AU" term="%22Yanke+AB%22">Yanke AB</searchLink>; Department of Orthopedics, Rush University Medical Center, Chicago, IL, USA. Electronic address: adam.yanke@rushortho.com.<br /><searchLink fieldCode="AU" term="%22Olcott+CW%22">Olcott CW</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Department of Orthopedics, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: chistopher_olcott@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Diekman+BO%22">Diekman BO</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Lampe Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, NC, USA. Electronic address: bdiekman@email.unc.edu.<br /><searchLink fieldCode="AU" term="%22Phanstiel+DH%22">Phanstiel DH</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC, USA; Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: douglas_phanstiel@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Loeser+RF%22">Loeser RF</searchLink>; Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Division of Rheumatology, Allergy and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address: richard_loeser@med.unc.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders+For+The+Osteoarthritis+Research+Society%22">W.B. Saunders For The Osteoarthritis Research Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9305697 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-9653 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210634584%22">10634584 </searchLink><i>NLM ISO Abbreviation: </i>Osteoarthritis Cartilage <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug
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