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Early fibrotic niches establish tumour-permissive microenvironments.

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Title: Early fibrotic niches establish tumour-permissive microenvironments.
Authors: Cardoso EC; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lee H; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., England FJ; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK., Cho H; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Lu R; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Varankar SS; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK., Park MS; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Rekhtman N; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Koo BK; Center for Genome Engineering, Institute for Basic Science, Daejeon, Republic of Korea., Simons BD; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Science, University of Cambridge, Cambridge, UK., Choi J; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. jinchoi@gist.ac.kr.; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. jinchoi@gist.ac.kr., Lee JH; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. leej49@mskcc.org.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. leej49@mskcc.org.
Source: Nature [Nature] 2026 May; Vol. 653 (8113), pp. 254-264. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cardoso+EC%22">Cardoso EC</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22England+FJ%22">England FJ</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cho+H%22">Cho H</searchLink>; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lu+R%22">Lu R</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Varankar+SS%22">Varankar SS</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Park+MS%22">Park MS</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Rekhtman+N%22">Rekhtman N</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Koo+BK%22">Koo BK</searchLink>; Center for Genome Engineering, Institute for Basic Science, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Simons+BD%22">Simons BD</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Science, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. jinchoi@gist.ac.kr.; Department of Life Sciences, Integrated Institute of Biomedical Research, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. jinchoi@gist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. leej49@mskcc.org.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. leej49@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 May; Vol. 653 (8113), pp. 254-264. <i>Date of Electronic Publication: </i>2026 Apr 22.
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