The association of epigenetic age acceleration with internal smoking dose, risk of lung cancer, and all-cause mortality in cigarette smokers: the Multiethnic Cohort study.

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Title: The association of epigenetic age acceleration with internal smoking dose, risk of lung cancer, and all-cause mortality in cigarette smokers: the Multiethnic Cohort study.
Authors: Liu T; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA., Loo LWM; Cancer Biology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA., Huang BZ; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA., Quon B; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA., Guillermo C; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA., Siegmund KD; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA., Wilkens LR; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA., Maunakea AK; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA., Hecht SS; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Murphy SE; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA., Stram DO; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA., Le Marchand L; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA., Binder AM; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.; Department of Epidemiology, University of California, Los Angeles, CA, USA., Park SL; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA. lpark@cc.hawaii.edu.
Source: Clinical epigenetics [Clin Epigenetics] 2026 Apr 22; Vol. 18 (1). Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The association of epigenetic age acceleration with internal smoking dose, risk of lung cancer, and all-cause mortality in cigarette smokers: the Multiethnic Cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Loo+LWM%22">Loo LWM</searchLink>; Cancer Biology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Huang+BZ%22">Huang BZ</searchLink>; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Quon+B%22">Quon B</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Guillermo+C%22">Guillermo C</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Siegmund+KD%22">Siegmund KD</searchLink>; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wilkens+LR%22">Wilkens LR</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Maunakea+AK%22">Maunakea AK</searchLink>; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Hecht+SS%22">Hecht SS</searchLink>; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Murphy+SE%22">Murphy SE</searchLink>; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Stram+DO%22">Stram DO</searchLink>; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Le+Marchand+L%22">Le Marchand L</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Binder+AM%22">Binder AM</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.; Department of Epidemiology, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Park+SL%22">Park SL</searchLink>; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA. lpark@cc.hawaii.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101516977 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-7083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218687075%22">18687075 </searchLink><i>NLM ISO Abbreviation: </i>Clin Epigenetics <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 22
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