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Thrombotic and thromboembolic events were not associated with tranexamic acid in three large randomized controlled trials.

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Title: Thrombotic and thromboembolic events were not associated with tranexamic acid in three large randomized controlled trials.
Authors: Brito AMP; Department of Surgery, Oregon Health and Science University, Portland, OR (A.M.P.B., J.E.K.); Department of Surgery, The Queen's Medical Center, Honolulu, HI (A.M.P.B.); Department of Surgery, HealthParners Regions, Saint Paul, MN (J.E.K.); Emergency Services, Alfred Health, Melbourne, Victoria (B.M.); School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria (B.M., S.B., J.L.S.); Department of Surgery, University of Pittsburgh, Pittsburgh, PA (M.D.N.); Australian Capital Territory, College of Health and Medicine, Australian National University, Canberra (R.G.); Department of Surgery, University of Nebraska Medical Center, Omaha, NE (C.D.B.); Molecular Neurotrauma and Hemostasis Group, Monash University, Melbourne, Victoria (R.M.); Department of Surgery, University of Chicago, Chicago, IL (S.R.); Uniformed Services University of the Health Sciences (M.A.S.)., Kenny JE, Mitra B, Neal MD, Gruen R, Barrett CD, Bernard S, Medcalf R, Rowell S, Sperry JL, Schreiber MA
Source: The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2026 Jul 01; Vol. 101 (1), pp. 48-56. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 101570622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-0763 (Electronic) Linking ISSN: 21630755 NLM ISO Abbreviation: J Trauma Acute Care Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Thrombotic and thromboembolic events were not associated with tranexamic acid in three large randomized controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Brito+AMP%22">Brito AMP</searchLink>; Department of Surgery, Oregon Health and Science University, Portland, OR (A.M.P.B., J.E.K.); Department of Surgery, The Queen's Medical Center, Honolulu, HI (A.M.P.B.); Department of Surgery, HealthParners Regions, Saint Paul, MN (J.E.K.); Emergency Services, Alfred Health, Melbourne, Victoria (B.M.); School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria (B.M., S.B., J.L.S.); Department of Surgery, University of Pittsburgh, Pittsburgh, PA (M.D.N.); Australian Capital Territory, College of Health and Medicine, Australian National University, Canberra (R.G.); Department of Surgery, University of Nebraska Medical Center, Omaha, NE (C.D.B.); Molecular Neurotrauma and Hemostasis Group, Monash University, Melbourne, Victoria (R.M.); Department of Surgery, University of Chicago, Chicago, IL (S.R.); Uniformed Services University of the Health Sciences (M.A.S.).<br /><searchLink fieldCode="AU" term="%22Kenny+JE%22">Kenny JE</searchLink><br /><searchLink fieldCode="AU" term="%22Mitra+B%22">Mitra B</searchLink><br /><searchLink fieldCode="AU" term="%22Neal+MD%22">Neal MD</searchLink><br /><searchLink fieldCode="AU" term="%22Gruen+R%22">Gruen R</searchLink><br /><searchLink fieldCode="AU" term="%22Barrett+CD%22">Barrett CD</searchLink><br /><searchLink fieldCode="AU" term="%22Bernard+S%22">Bernard S</searchLink><br /><searchLink fieldCode="AU" term="%22Medcalf+R%22">Medcalf R</searchLink><br /><searchLink fieldCode="AU" term="%22Rowell+S%22">Rowell S</searchLink><br /><searchLink fieldCode="AU" term="%22Sperry+JL%22">Sperry JL</searchLink><br /><searchLink fieldCode="AU" term="%22Schreiber+MA%22">Schreiber MA</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101570622%22">The journal of trauma and acute care surgery</searchLink> [J Trauma Acute Care Surg] 2026 Jul 01; Vol. 101 (1), pp. 48-56. <i>Date of Electronic Publication: </i>2026 Apr 23.
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  Data: Journal Article; Multicenter Study; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott%2C+Williams+%26+Wilkins%22">Lippincott, Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101570622 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2163-0763 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221630755%22">21630755 </searchLink><i>NLM ISO Abbreviation: </i>J Trauma Acute Care Surg <i>Subsets: </i>MEDLINE
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        Value: 10.1097/TA.0000000000005010
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              Text: 2026 Jul 01
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