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Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old.

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Title: Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old.
Authors: Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wang D; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Abbruzzese SM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine University of Washington, Seattle, WA, USA., Choi SH; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Beiser A; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Bressler J; Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada., Fohner AE; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Gibbs RA; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Heard-Costa N; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, USA., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Lacaze P; School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia., Le Grand Q; University of Bordeaux, INSERM, Bordeaux Population Health research center, UMR1219, Bordeaux, France., Lopez OL; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Mosley TH; The Memory Impairment and Neurodegenerative Dementia Center, University of Mississippi Medical Center, Jackson, MS, USA., Riaz M; School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia., Soumaré A; University of Bordeaux, INSERM, Bordeaux Population Health research center, UMR1219, Bordeaux, France., Yaqub A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Boerwinkle E; Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine University of Washington, Seattle, WA, USA.; Departments of Epidemiology and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Fornage M; Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Seshadri S; Glenn Biggs Institute for Alzheimer and Neurodegenerative Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., DeStefano AL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, USA.
Corporate Authors: TOPMed Neurocognitive Working Group, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Sequencing Project
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 Jun; Vol. 111 (4), pp. 1772-1782. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dupuis+J%22">Dupuis J</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.<br /><searchLink fieldCode="AU" term="%22Fohner+AE%22">Fohner AE</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ghanbari+M%22">Ghanbari M</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gibbs+RA%22">Gibbs RA</searchLink>; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Heard-Costa+N%22">Heard-Costa N</searchLink>; 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School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia.<br /><searchLink fieldCode="AU" term="%22Soumaré+A%22">Soumaré A</searchLink>; University of Bordeaux, INSERM, Bordeaux Population Health research center, UMR1219, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Yaqub+A%22">Yaqub A</searchLink>; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Boerwinkle+E%22">Boerwinkle E</searchLink>; Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Psaty+BM%22">Psaty BM</searchLink>; Cardiovascular Health Research Unit, Department of Medicine University of Washington, Seattle, WA, USA.; Departments of Epidemiology and Health Systems and Population Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Human Genetics Center, Department of Epidemiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; Glenn Biggs Institute for Alzheimer and Neurodegenerative Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22DeStefano+AL%22">DeStefano AL</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2026 Jun; Vol. 111 (4), pp. 1772-1782. <i>Date of Electronic Publication: </i>2026 Apr 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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