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Targeting the FOXO4-p53 axis by retro-inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline.

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Title: Targeting the FOXO4-p53 axis by retro-inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline.
Authors: Alameen AAM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, P.O. Box 2014, Sakaka, KSA, Saudi Arabia. aaalameen@ju.edu.sa., Al-Kuraishy HM; Department of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq., Fawzy MN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Arish Branch, Sinai University, Arish, 45511, Egypt. mohamed.naser@su.edu.eg., Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt. Gaberelsaberbatiha@gmail.com.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Apr 23. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Alameen+AAM%22">Alameen AAM</searchLink>; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, P.O. Box 2014, Sakaka, KSA, Saudi Arabia. aaalameen@ju.edu.sa.<br /><searchLink fieldCode="AU" term="%22Al-Kuraishy+HM%22">Al-Kuraishy HM</searchLink>; Department of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq.<br /><searchLink fieldCode="AU" term="%22Fawzy+MN%22">Fawzy MN</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Arish Branch, Sinai University, Arish, 45511, Egypt. mohamed.naser@su.edu.eg.<br /><searchLink fieldCode="AU" term="%22Batiha+GE%22">Batiha GE</searchLink>; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt. Gaberelsaberbatiha@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 Apr 23. <i>Date of Electronic Publication: </i>2026 Apr 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00210-026-05309-6
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              Text: 2026 Apr 23
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